Post-exposure Influenza Prophylaxis in a Hospital Setting

Post-Exposure Influenza Chemoprophylaxis With Oseltamivir for Five Days vs Ten Days in Acute-Care Hospital: a Non-Inferiority Randomized Open-Label Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07496736

Enrollment

200

Registered

2026-03-27

Start date

2025-12-01

Completion date

2028-03-31

Last updated

2026-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza

Brief summary

The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza in a hospital setting.

Interventions

DRUGOseltamivir

oseltamivir 5 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years or older * exposure to influenza during hospitalization * risk factors for influenza complications * consent for participation obtained

Exclusion criteria

* younger than 18 years * hematological malignancy * hospitalized in intensive care unit * refusal to participate

Design outcomes

Primary

Measure	Time frame
frequency of influenza	10 days after completing prophylaxis

Countries

Slovenia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 1, 2026