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Effects of Post-Isometric Relaxation and Myofascial Release on Low Back Pain With Lower Cross Syndrome

Combined Effects of Post-Isometric Relaxation and Myofascial Release in Patients With Low Back Pain and Lower Cross Syndrome: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07496099
Enrollment
60
Registered
2026-03-27
Start date
2026-08-25
Completion date
2027-03-20
Last updated
2026-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hamstring Muscle Tightness, Low Back Pain, Mechanical, Lower Cross Syndrome

Keywords

Hamstring Tightness, Post-Isometric Relaxation with Myofascial Release, low back pain with lower cross syndrome

Brief summary

This randomized controlled trial aims to evaluate the combined effects of post-isometric relaxation and myofascial release on pain, flexibility, and functional disability in individuals with low back pain associated with lower cross syndrome. Eligible participants aged 18 to 45 years will be randomly allocated into two parallel intervention groups. One group will receive post-isometric relaxation combined with myofascial release, while the comparison group will receive conventional stretching combined with Therapeutic modalities. Outcomes will be assessed at baseline and after completion of the intervention period. The results of this study are expected to contribute to evidence-based physiotherapy management of low back pain associated with postural imbalance.

Interventions

OTHERpost isometric relaxation

Post-isometric relaxation will be applied to the hamstring muscles. Participants will be positioned supine with the hip flexed to 90 degrees and will perform a submaximal isometric contraction of the hamstrings against therapist resistance for 5 to 8 seconds, followed by a passive stretch of approximately 10 seconds. The procedure will be repeated three times per limb per session.

OTHERMYOFASCIAL RELEASE

Myofascial release will be applied to the hamstring muscles with the participant in a prone position. Sustained manual pressure will be applied along the length of the hamstring muscles using the therapist's hands for approximately 30 seconds per application, repeated multiple times per session to improve tissue extensibility.

OTHERConventional Static Stretching

Conventional static stretching of the hamstring muscles will be performed with the participant in a supine position. Each stretch will be held for approximately 30 seconds and repeated three times per limb per session as part of routine physiotherapy management.

OTHERTherapeutic Modalities

Therapeutic modalities, including ultrasound therapy or superficial heat application using a heating pad, will be applied prior to stretching to reduce pain and improve tissue extensibility as part of conventional physiotherapy care.

Sponsors

University of Karachi
Lead SponsorOTHER
IQRA University
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

This study will be single-blinded. The outcome assessor will be blinded to group allocation to minimize assessment bias. Due to the nature of the interventions, participants and treating physiotherapists cannot be blinded.

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

1. Participants aged 18-45 years old 2. having low back pain persisting for at least 4 weeks 3. with clinical diagnosis of LCS, and hamstring tightness (AKE \>15°)

Exclusion criteria

1. Participants with the history of spinal surgery active neurological conditions 2. systemic disease affecting connective tissue (Rheumatoid arthritis, Systemic lupus erythematosus) 3. recent lower limb or spinal injury (within 6 months) 4. pregnancy or inability to lie prone for treatment.

Design outcomes

Primary

MeasureTime frameDescription
Hamstring FlexibilityOutcome measures will be assessed at baseline, immediately after the first session, after 36 sessions at 12 weeks (3 months), and after 72 sessions at 24 weeks (6 months)Hamstring flexibility will be assessed using Active Knee Extension (AKE) test measured in degrees with a goniometer.

Secondary

MeasureTime frameDescription
Pain Intensityassessed at baseline, immediately after the first session, after 36 sessions at 12 weeks (3 months), and after 72 sessions at 24 weeks (6 months)Pain intensity will be assessed using the Visual Analogue Scale for Pain, a 10-centimeter scale ranging from 0 to 10, where: 0 = no pain 10 = worst imaginable pain Higher scores indicate worse pain intensity.
functional flexibility(Straight Leg Raise Test)Outcome measures will be assessed at baseline, immediately after the first session, after 36 sessions at 12 weeks (3 months), and after 72 sessions at 24 weeks (6 months)Functional flexibility will be assessed using the Straight Leg Raise (SLR) Test, measured in degrees using a goniometer.
Posture Assessment (REEDCO Posture Scale)Outcome measures will be assessed at baseline, immediately after the first session, after 36 sessions at 12 weeks (3 months), and after 72 sessions at 24 weeks (6 months)Posture will be assessed using the REEDCO Posture Scale, a standardized observational scale used to evaluate body posture. The scale ranges from 0 to 100, where: Lower scores indicate poor posture Higher scores indicate better posture alignment

Countries

Pakistan

Contacts

CONTACTBushra Madad Ali Malik, MPHIL
bushramalik0910@gmail.com+92305 2722589
CONTACTAftab Ahmed Mirza Baig, PhD
dr.aftab@iqra.edu.pk+923002739920
STUDY_CHAIRBasit Ansari, PhD

University of Karachi

PRINCIPAL_INVESTIGATORBushra Madad Ali Malik, DPT

University of Karachi

STUDY_DIRECTORAftab Ahmed Mirza Baig, PhD

IQRA University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 29, 2026