Stroke
Conditions
Brief summary
Walking impairment following neurologic injury can increase the energy cost of walking threefold, acting as a functional barrier to independence. The goal of this cross-sectional study is to determine the measurement properties of a novel biomechanical cost of walking measure in chronic stroke capable of pinpointing the origins of movement inefficiencies. This research aims to: 1. determine the convergent validity of biomechanical cost of walking with functional measures in relation to metabolic cost of walking, 2. determine the reliability of biomechanical cost of walking in relation to metabolic cost of walking, 3. determine the responsiveness of biomechanical cost of walking in relation to metabolic cost of walking. Individuals with walking impairment from stroke will complete three 5-minute comfortable speed treadmill walking trials. The 3rd walking trial will be against resistance to increase cost of walking. This single session study will compare the metric properties of biomechanical cost of walking in relation to metabolic cost of walking.
Interventions
BEHAVIORALResisted walking
Comfortable speed treadmill walking with resisted forward progression.
Sponsors
University of Cincinnati
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age 30-80 years at the time of consent * Hemiparesis from ischemic and/or hemorrhagic strokes * Most recent stroke for which participant sought treatment, at least 3 months prior to study consent * Walking speed \<1.0 m/s on the 10-meter walk test * Able to walk 10m over ground with assistive devices as needed * Able to walk at least 5 minutes continuously on the treadmill ≥ 0.1 mile per hour * No contraindications to exercise according to ACSM guidelines * Able to communicate with investigators, follow a 2-step command and correctly answer consent comprehension questions
Exclusion criteria
* Hospitalization for cardiac or pulmonary disease within past 3 months * Implanted pacemaker or defibrillator * Severe lower limb hypertonia (Ashworth \>2) * Foot drop or lower limb joint instability without adequate stabilizing device * Clinically significant neurologic disorder other than stroke * Other significant medical condition likely to jeopardize safety (e.g. joint contracture, gait limited by pain) * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Constituent Lower Extremity Work | 1st minute and 5th minute of resisted walking trial versus non-resisted walking trial. | Energy expenditure calculated using biomechanical variables such as force and limb motion |
| Metabolic Cost of Walking | 1st minute and 5th minute of resisted walking trial versus non-resisted walking trial. | Energy expenditure calculated using oxygen consumption and carbon dioxide production |
Countries
United States
Contacts
CONTACTChristina Garrity, DPT
PRINCIPAL_INVESTIGATORChristina Garrity, DPT
University of Cincinnati
Outcome results
None listed