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Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities

Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities: Effects on Esthetic Perceptions of Children and Their Parents

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07494682
Enrollment
64
Registered
2026-03-27
Start date
2024-05-06
Completion date
2024-12-20
Last updated
2026-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enamel Hypomineralization, Molar Incisor Hypomineralisation, Tooth Discoloration

Keywords

Molar incisor hypomineralization, Resin infiltration technique, Etch bleach seal technique, Minimally invasive treatment, Esthetic perception

Brief summary

This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents. Participants with MIH-affected incisors received either resin infiltration or etch-bleach-seal treatment. Esthetic outcomes and satisfaction levels were assessed using standardized scales.

Detailed description

Molar-incisor hypomineralization (MIH) is a qualitative enamel defect that often leads to esthetic concerns, particularly in anterior teeth. Minimally invasive treatment approaches such as resin infiltration and etch-bleach-seal techniques have been proposed to improve the appearance of MIH opacities. This study aimed to compare the effectiveness of these two approaches in masking MIH opacities in permanent incisors and to evaluate esthetic perceptions from both children and their parents. Esthetic perceptions related to dental appearance were evaluated using the ''Child's and Parent's Questionnaire about Teeth Appearance''. The color masking effectiveness of resin infiltration and the etch-bleach-seal (EBS) technique on MIH-related anterior enamel opacities were evaluated using a spectrophotometer (VITA Easyshade® V, Sackingen, Germany). The findings are expected to contribute to evidence-based decision-making for minimally invasive esthetic management of MIH.

Interventions

OTHERResin infiltration

A minimally invasive dental procedure used to mask enamel opacities associated with molar incisor hypomineralization. The technique involves etching the enamel surface, drying with ethanol, and applying a low-viscosity resin infiltrant (Icon®, DMG), followed by light curing and polishing in a single clinical session.

OTHEREtch Bleach Seal Technique

A minimally invasive dental procedure used to improve the appearance of enamel opacities associated with molar incisor hypomineralization. The technique includes phosphoric acid etching, application of sodium hypochlorite for bleaching, and sealing with a resin-based sealant, followed by light curing and polishing in a single clinical session.

Sponsors

Pamukkale University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Masking description

Due to the nature of the clinical procedures, blinding of the operator was not possible. To minimize potential assessment bias, the evaluation of esthetic perception questionnaires completed by children and their parents were performed by another investigator who was blinded group allocation. In addition, children and their parents were not informed about the specific treatment technique applied and informed only that a minimally invasive esthetic procedure would be performed.

Eligibility

Sex/Gender
ALL
Age
8 Years to 10 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 8 and 10 years, * Diagnosis of MIH according to the European Academy of Paediatric Dentistry (EAPD) criteria \[19\], with at least one permanent incisor exhibiting well-demarcated white-cream and/or yellow-brown enamel opacities causing esthetic concern to the child and/or parents, * Absence of urgent dental treatment needs, with completed treatment of posterior teeth, * Ability of both children and parents to read and understand Turkish.

Exclusion criteria

* Presence of urgent dental treatment or requirement for restorative treatment of MIH affected permanent first molars during the study period, * Presence of dental or facial anomalies other than MIH (e.g. hypodontia, cleft lip and/or palate), * Presence of dental caries, crown fractures, or extrinsic/intrinsic tooth discolorations that could compromise esthetic perception, * Presence of other developmental enamel defects (e.g. enamel hypoplasia, amelogenesis imperfecta, fluorosis, or hypoplasia related to previous dental trauma), * Previous restorative treatment, resin infiltration, microabrasion, and/or tooth whitening on the affected incisors, * Children and/or parents who were unlikely to attend follow-up visits or were unable to read and understand Turkish.

Design outcomes

Primary

MeasureTime frameDescription
Change in esthetic perception of children and parentsBaseline and 3 monthsEsthetic perception was assessed using the Child's and Parent's Questionnaire about Teeth Appearance. Changes in physical, psychological, and social domains, as well as satisfaction with tooth appearance, were evaluated before treatment and at 3-month follow-up.

Secondary

MeasureTime frameDescription
Color change of MIH-related anterior enamel opacitiesBaseline, 1 month, 3 monthsColor changes were measured using a spectrophotometer based on the CIELAB system. Color differences (ΔE values) were calculated to assess the effectiveness of masking enamel opacities.

Countries

Turkey (Türkiye)

Contacts

STUDY_DIRECTORArif Bolaca, Dr

Pamukkale University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 29, 2026