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Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis

A Retrospective Study: Complete vs Partial Mesh Removal for Mesh Infection After Hernioplasty - Clinical Outcomes and Pathogen Analysis

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07491250
Enrollment
100
Registered
2026-03-24
Start date
2026-03-18
Completion date
2026-07-31
Last updated
2026-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal Hernia Repair, Mesh Infection

Keywords

Inguinal hernia repair, mesh infection, complete mesh removal, partial mesh removal

Brief summary

Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients. Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.

Detailed description

We conducted a single-center, retrospective case series analysis. We included patients who developed mesh infection after tension-free IHR and underwent surgical treatment at our center between January 2016 and December 2025. Patients with mesh infection after incisional, parastomal, or umbilical hernia repair were excluded. We also excluded patients who improved with conservative treatment and did not undergo surgery. We collected the following data: demographic characteristics, comorbidities, laboratory and imaging results, characteristics of the primary hernia surgery, infection characteristics, intraoperative data, and postoperative outcomes. All data were entered into a standardized database. Follow-up was conducted through outpatient visits and telephone interviews. The last follow-up was on October 30, 2025.

Interventions

PROCEDUREComplete mesh removal

Total explantation of the entire prosthetic mesh, including all visible portions and fixation sutures, regardless of the extent of infection.

PROCEDUREPartial mesh removal

Excision of only the infected or non-incorporated portion of the mesh, with preservation of the well-incorporated, uninfected segment left in situ.

Sponsors

Fudan University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

1. Patients who underwent tension-free inguinal hernioplasty with mesh placement. 2. Patients diagnosed with mesh infection requiring surgical re-intervention. 3. Patients who underwent complete or partial mesh removal surgery. 4. Availability of complete medical records and follow-up data.

Exclusion criteria

1. Patients with mesh infection managed conservatively (without surgical removal). 2. Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up). 3. Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair). 4. Patients lost to follow-up immediately after discharge (no postoperative assessment).

Design outcomes

Primary

MeasureTime frameDescription
Hernia Recurrence RateFrom date of surgery to December 2025Presence of clinically or radiologically confirmed recurrent inguinal hernia at the site of previous hernioplasty following mesh removal surgery.
Infection Recurrence RateFrom date of surgery to December 2025Recurrence of surgical site infection at the same location after initial surgical treatment for mesh infection, confirmed by clinical signs (e.g., erythema, purulent drainage, sinus tract formation) and/or positive microbiological culture.

Contacts

CONTACTXiaoyu Peng, MD
23211280025@m.fudan.edu.cn+8619121706827

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026