Skip to content

URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS

FACTORS ASSOCIATED WITH URINARY INCONTINENCE AND EVALUATION OF PELVIC FLOOR MUSCLE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS: CROSS-SECTIONAL STUDY

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07489794
Acronym
MS-UI-PFM
Enrollment
47
Registered
2026-03-24
Start date
2026-03-09
Completion date
2026-10-30
Last updated
2026-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Urinary Incontinence (UI)

Keywords

multiple sclerosis, urinary incontinence, Electromyography, Fatigue, Physical Activity

Brief summary

This study aims to investigate the relationship between urinary incontinence severity and surface electromyography (EMG) findings in women with multiple sclerosis. It will also examine the association of urinary incontinence with disability, quality of life, physical activity, and fatigue.

Detailed description

This study investigates the relationship between urinary incontinence (UI) severity and pelvic floor muscle activity in women with multiple sclerosis (MS). UI is common in MS and negatively affects quality of life, physical activity, and social participation. The study also explores how UI severity is associated with disability, fatigue, and overall quality of life. Participants' demographic and clinical information, including age, disease duration, MS type, and disability level (measured by the Expanded Disability Status Scale, EDSS), will be recorded. Standardized questionnaires will assess urinary symptoms, their impact on daily life, physical activity, and fatigue. Pelvic floor muscle activity will be evaluated using surface electromyography (EMG) with biofeedback, conducted by trained physiotherapists. The study will be conducted at the Pelvic Floor Health Center and is planned as a cross-sectional study. All assessments, including questionnaires and EMG measurements, are expected to take approximately 45 minutes per participant. Findings from this study aim to improve understanding of UI in women with MS and guide future interventions.

Interventions

None listed

Sponsors

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
30 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Diagnosis of multiple sclerosis (MS) according to the 2017 revised McDonald criteria. Female patients aged 30-50 years (age range with higher prevalence of urinary incontinence in MS). Experiencing urinary incontinence (UI) symptoms according to the International Continence Society (ICS) definition. EDSS (Expanded Disability Status Scale) score below 6.5. Patients with no communication difficulties. -

Exclusion criteria

MS patients who do not provide consent to participate in the study. MS patients who have had a medication change within the last 6 months. Pregnant MS patients. History of vaginal or cesarean delivery within the last 6 months. Pelvic organ prolapse. Urinary tract infection \-

Design outcomes

Primary

MeasureTime frameDescription
Pelvic floor muscle activity with surface EMGbaselineEvaluated using biofeedback-assisted surface EMG. Metrics recorded include mean EMG activity during contraction and rest phases, standard deviation of EMG activity, peak and minimum EMG values, contraction onset, and relaxation times

Secondary

MeasureTime frameDescription
International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)baselineAssesses severity and impact of urinary incontinence
Incontinence Impact Questionnaire (IIQ-7)baselineEvaluates the effect of urinary incontinence on quality of life
International Physical Activity Questionnaire (IPAQ)baselineAssesses participants' physical activity levels
Fatigue Severity Scale (FSS)baselineMeasures severity of fatigue experienced by participants

Countries

Turkey (Türkiye)

Contacts

CONTACTBüşra Aydın Erkılıç, MSc
bsrr.aydinn@gmail.com905062214052

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026