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Impact of Sleep Restriction on Blood Pressure Reactivity

Impact of Sleep Restriction on Blood Pressure Reactivity

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07489417
Enrollment
45
Registered
2026-03-24
Start date
2026-03-04
Completion date
2027-08-01
Last updated
2026-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Sleep

Keywords

Sleep, Blood pressure

Brief summary

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

Interventions

BEHAVIORALSleep Restriction

You will be asked to shorten your sleep to four hours.

Sponsors

University of Missouri-Columbia
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy adult men and women * 18-45 years of age * BMI \< 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group) * Non-pregnant, non-breastfeeding, and non-nicotine users * Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight * Premenopausal

Exclusion criteria

* No acute or chronic conditions * Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function * Self-reported history of irregular sleep * Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Design outcomes

Primary

MeasureTime frameDescription
Mean Blood PressureBaseline and during the last 1-minute of stressMean Blood pressure

Countries

United States

Contacts

CONTACTJacqueline Limberg
limberglab@missouri.edu1-573-882-2544

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 29, 2026