Dementia
Conditions
Keywords
Phototherapy, Complex dementia
Brief summary
The purpose of this research is to determine whether the use of phototherapy can help reduce behavioral and psychological symptoms, including agitation in people with dementia.
Interventions
OTHERPhototherapy
Bright light therapy will be provided via the Verilux HappyLight. The unit will be placed on a mobile bedside table, at eye level, 60 cm from the patient. Patients will receive phototherapy in 60 minute sessions, 3 times daily for 5 days.
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients admitted on the inpatient Domitilla 3D or 4D unit. * Documented diagnosis of dementia or suspected major neurocognitive disorder. * Presence of BPSD symptoms either clinician documented in EHR or assessed through CMAI-O form * Have patient consent or have a LAR able to sign the consent on behalf of the patient.
Exclusion criteria
* Macular degeneration, blindness, or photosensitivity * Patients that do not have capacity to consent and do not have a legally authorized representative to consent on their behalf * Recent eye surgery * Bipolar disorder * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility of 5-day phototherapy protocol | Day 5 | Feasibility will be defined as the percentage of eligible patients who choose to enroll in the study out of total patients approached. |
| Acceptability of 5-day phototherapy protocol | Day 5 | Accessibility will be defined as the percentage of study participants to complete at least one session per day of the 5-day protocol |
| Tolerability of 5-day phototherapy protocol | Day 5 | Tolerability will be defined as percentage of patients to rate phototherapy as 'very tolerable' based on being asked "Considering all aspects of your experience, how would you rate the overall tolerability of the phototherapy?" The response options are: very tolerable, somewhat tolerable, neutral, somewhat intolerable, and very intolerable. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sleep duration | Day 5 | Sleep duration will be reported by nursing staff in hours. |
Countries
United States
Contacts
CONTACTMelanie Gentry, MD
CONTACTDonna Lawson
PRINCIPAL_INVESTIGATORStephanie P. Chambers, APRN, CNS
Mayo Clinic
Outcome results
None listed