Laparoscopic Cholecystectomy
Conditions
Brief summary
The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).
Interventions
DRUGLactated Ringer 500ml
500ml ringer lactate perioperatively given in laparoscopic cholecystectomy patients as compared to traditional 1000ml fluid
DRUGLactated Ringer 1000ml
1000ml iv fluid given perioperatively in laparoscopic cholecystectomy
Sponsors
King Edward Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* All patients undergoing elective cholecystectomy * Age : 18-60 years * All genders * ASA class 1 and 2
Exclusion criteria
* History of previous laparotomy * Perforated gall bladder * Duration of surgery more than 3 hours * More than 100ml intra operative blood loss
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean Systolic Blood Pressure | Day 1 | Mean systolic blood pressure at preoperative and 3,6, 12 and 24 hours post operatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean Pulse Rate Per Minute | Day 1 | Mean pulse rate per minute at pre operative, 3,6,12 and 24 hours post operatively |
| Mean Diastolic Blood Pressure | Day 1 | Mean diastolic blood pressure at pre operative, 3,6,12 and 24 hours post operatively |
| Mean Pulse Pressure | Day 1 | Mean pulse pressure at pre operative, 3,6,12 and 24 hours post operatively |
Countries
Pakistan
Outcome results
None listed