Oxygen, Oxygen Saturation
Conditions
Keywords
oxygenation, Posterior Stabilization Surgery, Mechanical Ventilation Parameters, optic nerve sheath diamater
Brief summary
This study aims to evaluate the effects of prone positioning on oxygenation, ventilation, and hemodynamic parameters in patients undergoing posterior stabilization surgery under general anesthesia. By comparing routine anesthesia and monitoring data obtained in the supine and prone positions, the study seeks to determine how positional changes influence respiratory mechanics and perioperative physiological stability.
Detailed description
The prone position is frequently used during posterior stabilization surgery, yet it is associated with important physiological changes that may affect both respiratory and hemodynamic function under general anesthesia. Previous studies have shown that prone positioning may improve ventilation-perfusion matching, increase functional residual capacity, and enhance oxygenation. At the same time, position-related alterations in thoracic mechanics, airway pressures, venous return, and cardiovascular parameters may influence intraoperative management. This study is designed to comprehensively assess the physiological effects of prone positioning in anesthetized patients undergoing posterior stabilization surgery. Routine anesthesia and monitoring data collected during mechanical ventilation will be analyzed and compared between the supine and prone positions. Particular focus will be placed on oxygenation, ventilation variables, respiratory mechanics, and hemodynamic parameters in order to evaluate the impact of positional change. In addition, the study aims to identify which clinical and monitoring findings should be prioritized during anesthetic management of patients in the prone position. By clarifying the relationship between positioning and perioperative physiological responses, the study seeks to contribute to safer anesthetic practice and to support the maintenance of adequate oxygenation and hemodynamic stability throughout surgery.
Interventions
OTHERblood gase
Arterial blood gas samples will be obtained from patients, and alveolar oxygenation ratios will be compared between the supine and prone positions.
Sponsors
Sakarya University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Patients aged 18 to 75 years Patients classified as ASA physical status I, II, or III according to the American Society of Anesthesiologists Patients undergoing posterior stabilization surgery Patients who voluntarily agreed to participate in the study Patients with a body mass index (BMI) \<35 kg/m² Patients followed with a standard mechanical ventilation procedure
Exclusion criteria
* \- ASA 4 olarak değerlendirilenler * Anestezik ajan alerjisi olanlar * Kanama diatezi bozukluğu olanlar * Cerrahi süresi 3 saatin üstünde olanlar * Bilinen ileri akciğer hastalığı olanlar (intertisyel akciğer hastalığı, ileri düzey KOAH, ileri düzey astım vb) * VKI≥35 olanlar * Obstrüktif uyku apne sendromu tanısı olanlar * Toraks deformitesi olanlar * Ciddi kalp yetmezliği öyküsü olanlar (EF\<30) * Şiddetli anemi öyküsü olanlar (Hg\<8 mg/dl) * Cerrahi operasyon sırasında kan transfüzyonu ihtiyacı olan hastalar
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in alveolar oxygenation between supine and prone positions | within 20 minutes after anesthesia induction | The primary outcome of this study is to evaluate the difference in alveolar oxygenation between the supine and prone positions in patients undergoing posterior stabilization surgery. Arterial blood gas samples obtained during surgery will be used to compare oxygenation parameters measured in both positions and to assess the effect of positional change on oxygenation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in optic nerve sheath diameter between supine and prone positions | intraoperatively | The secondary outcome is the comparison of optic nerve sheath diameter measurements obtained in the supine position and after positioning the patient prone during posterior stabilization surgery. This assessment is intended to evaluate the effect of positional change on optic nerve sheath diameter. |
Countries
Turkey (Türkiye)
Contacts
CONTACTHAVVA KOCAYİĞİT, Associate Professor
Outcome results
None listed