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A Pilot Project for PLWH Aged 65-75: Preventing the Development of Frailty

A Pilot Project for PLWH Aged 65-75: Preventing the Development of Frailty

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07486661
Acronym
Frailty
Enrollment
100
Registered
2026-03-20
Start date
2025-08-28
Completion date
2028-07-01
Last updated
2026-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age Group: 65-74, HIV

Keywords

HIV, frailty, ageing

Brief summary

In ageing populations, the main risk is the development of a syndrome of frailty, characterized by the addition of polymorbidity, polymedication, psychosocial difficulties, cognitive disorders, ... This functional decline is linked to a reduction in the person's functional reserves, and will lead to an increase in health problems, hospitalizations and, ultimately, mortality. People living with HIV (PLWH) over 50 develop the same kind of comorbidities as HIV-uninfected people over 75 years-old. In Belgium, the care of PLWH\< 75 years with frailty syndrome is not reimbursed by healthcare insurance, and geriatric assessment and management is therefore not possible in this age group, despite the very real need. Goals of this project are: 1. Determine the proportion and characterize the population of PLWH aged 65 and over who screen positive using the Fried scale 2. Validate the application of the Fried scale in a population of PLWH 3. Offer a care pathway model to prevent the onset of frailty in people screened as at-risk and who do not benefit from routine screening or care pathway reimbursement. Projets proposal: * Systematic screening of all PLWH aged 65-74 at the MIA Center, by the nurse prior to physician consultation, using the Fried scale. * Send all PLWH aged 65-74 who screen positive to Geriatric One Day for an ergo-geriatric consultation to confirm the risk of frailty and set up a preventive care pathway * After treatment, perform a patient satisfaction questionnaire + a new Fried scale at one year

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire Saint Pierre
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to 74 Years
Healthy volunteers
No

Inclusion criteria

* living with HIV * between 65-74 years

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
number of PLWH between 65 and 74 years with frailtyBaselineUsing Fried scale and complete geriatic assesment The Fried scale is a widely recognized assessment tool designed to evaluate frailty in older adults, particularly those aged 65 and above. It helps identify individuals at increased risk of adverse health outcomes, such as falls, hospitalization, disability, and mortality. The assessment is based on five key criteria: unintentional weight loss, exhaustion, low physical activity, slowness, and weakness, with each positive criterion scoring one point. Scores of 0 indicate a robust individual, 1-2 suggest a state of pre-frailty, and ≥3 confirm frailty.

Secondary

MeasureTime frameDescription
Number of PLWH with a Fried test detecting frailtyBaselineFried scale
Number of PLWH with Fried scale detecting pre-frailty conditionBaselineFried scale
Results of Fried scale at one yearone year after the first Fried scale performed at baselineFried scale performed one year after the first Fried scale in those with a abnormal Fried scale at baseline ( \>/=2)

Countries

Belgium

Contacts

CONTACTAgnes LIBOIS, MD
maladiesinfectieuses@stpierre-bru.be+3225354130
CONTACTCharlotte Martin, MD, PHD
maladiesinfectieusess@stpierre-bru.be+3225354130

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026