Parkinson's Disease (PD)
Conditions
Keywords
Deep brain stimulation, Local field potentials, Parkinson's disease
Brief summary
The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is: Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection? Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.
Interventions
None listed
Sponsors
Loes Laurijssen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Voluntary written informed consent of the participant 2. At least 18 years of age at the time of signing the Informed Consent Form (ICF) 3. Diagnosis of idiopathic Parkinson's disease according to the clinical diagnostic criteria of the Movement Disorder Society (MDS) 4. Eligible for DBS to treat refractory PD motor symptoms, as based on multidisciplinary DBS screening 5. Have sufficient understanding of the Dutch and French language to participate in the study
Exclusion criteria
* /
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alignment of contact selection | From the first LFP recording to the last LFP recording (6 - 9 months) | Alignment between local field potential-based contact selection and the clinically optimized stimulation contact. |
Countries
Belgium
Contacts
CONTACTBart Swinnen, MD, PhD
Outcome results
None listed