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Dementia in Fiction and Clinical Narratives

Examining Representations of Dementia in Fiction and Clinical Narratives

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07482800
Enrollment
40
Registered
2026-03-19
Start date
2026-03-17
Completion date
2026-07-31
Last updated
2026-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer s Disease, Dementia

Keywords

Dementia, Language Decline, Neurology, Narrative Medicine, Literary Analysis

Brief summary

This study aims to compare the natural narrative language of patients with Alzheimer's disease and the fictional depictions of dementia in contemporary novels from both neurological and literary perspectives. It investigates the similarities and differences in the deterioration of semantic and episodic memory. The goal is to develop a cross-disciplinary language observation model that enhances early diagnostic understanding, fosters empathy in caregiving, and strengthens medical humanities education.

Detailed description

Background: Dementia is a major neurodegenerative disease of concern in aging societies worldwide, with Alzheimer's disease being the most common form. Early symptoms often involve language impairments and narrative disorganization. While neurology has extensively studied semantic memory and pragmatic dysfunction, systematic analysis of natural language narratives remains limited. Meanwhile, contemporary "neuronovels" depict the linguistic and cognitive decline of characters with dementia in highly realistic and emotionally resonant ways, providing narrative insights that may complement clinical observations. This project uses novels such as The Tunnel by A. B. Yehoshua and Still Alice by Lisa Genova as key texts, integrating real patient data and neurobehavioral assessments to construct a model that bridges clinical and literary approaches. Study Design: This is a one-year prospective study. Methods: Semi-structured interviews will be conducted to collect spontaneous narratives focusing on childhood memories, life events, and self-description. Audio recordings will be transcribed and analyzed for linguistic features and behaviors. In parallel, fictional narratives from selected dementia-themed novels will be analyzed for language disruption, narrative fragmentation, and identity construction in characters with dementia. A multidisciplinary team will conduct cross-comparative analyses between clinical data and literary texts to establish a reference framework of language decline and narrative behavior for future diagnostic support and empathy training.

Interventions

None listed

Sponsors

Fu Jen Catholic University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

* Diagnosed with early-stage Alzheimer's disease or other mild cognitive impairment by a neurologist (case group) / healthy individuals matched for age and education level (control group) * Able to communicate and understand basic language

Exclusion criteria

* Refuse to participate in the study

Design outcomes

Primary

MeasureTime frameDescription
Mini-Mental State Examinationon the day of enrollmentassess cognitive function, including orientation, memory, attention, language, and basic visuospatial ability

Countries

Taiwan

Contacts

CONTACTKe-Yun Chao, PhD
ck_qq@hotmail.com+886-905-301-879
PRINCIPAL_INVESTIGATORKe-Yun Chao, PhD

Fu Jen Catholic University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026