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Effects of Core Stabilization Exercises in Female Patients With Gonarthrosis

Randomized Controlled Study of the Effects of Core Stabilization Exercises in Addition to Knee Exercises in Female Patients With Gonarthrosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07482332
Enrollment
40
Registered
2026-03-19
Start date
2026-01-05
Completion date
2026-09-14
Last updated
2026-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis (Knee OA)

Keywords

Knee osteoarthritis, Core stabilization exercise, Physiotherapy, Function

Brief summary

Osteoarthritis (OA) is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, primarily affecting weight-bearing joints. Individuals with knee osteoarthritis exhibit weakness in the trunk and periarticular muscles. This loss of strength in the trunk and periarticular muscles increases the load on the joint, contributing to the development and progression of the disease. This study aimed to investigate the effects of core stabilization, applied in addition to knee muscle exercise programs, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.

Detailed description

Osteoarthritis is the most common chronic joint disease and a leading cause of disability worldwide. It represents a significant public health and cost problem due to reduced work productivity and early retirement. OA is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, particularly in weight-bearing joints, along with a series of biochemical and morphological changes. While its etiology is not fully understood, it is considered a multifactorial disease involving a combination of systemic and regional factors. Increased bone density, joint laxity, and excessive mechanical loading are some of these factors. Symptoms of knee osteoarthritis include pain, joint stiffness, swelling, loss of function, and muscle weakness. Pain and joint stiffness in individuals negatively affect daily living activities such as climbing stairs, walking, and running, leading to decreased functionality. Current literature emphasizes that strong proximal trunk stabilization is needed for safe and effective completion of movements in the distal segments, and that weakness in this region is directly related to lower extremity pain. This study aimed to investigate the effects of core stabilization, applied in addition to an exercise program for the knee muscles, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.

Interventions

OTHER10 days of conventional physiotherapy (Hot Pack, TENS, Ultrasound) and 6 weeks of routine knee exercises

For 10 days, conventional physical therapy consisting of Hot Pack, TENS, Ultrasound, and routine knee strengthening exercises was applied in the hospital. These knee exercises were continued for four weeks after the hospital treatment period.

OTHERSix weeks of core stabilization exercises.

For six weeks, Warner et al. A core stabilization exercise protocol, as defined by was provided. This protocol included neutral spine position in hook position, activation of deep abdominal muscles, supine bridge, ipsilateral and contralateral limb movements in hook position, abdominal curl (sit-up), bridge (double and single leg), plank on knees, side plank on knees, clam exercise (without resistance), and modified 100 exercises. The exercises were performed 3 days a week, with 10 repetitions each.

Sponsors

Cumhuriyet University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Intervention model description

Paralel Randomized

Eligibility

Sex/Gender
FEMALE
Age
45 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Kellgren-Lawrence 2-3 knee osteoarthritis * Female patient aged 40-65 * Volunteer

Exclusion criteria

* Having received physical therapy within the last month * Presence of neurological, cardiac, and respiratory problems * Less than 90 degrees of flexion in the knee and hip joints * Presence of any pathology in the lower extremity that may affect balance and function * History of lower extremity surgery * Severe visual, hearing, and speech impairment * Illiteracy in Turkish * Body mass index of 30 or higher

Design outcomes

Primary

MeasureTime frameDescription
Sit UpsBaseline-6 weeks follow-upParticipants are positioned supine with knees flexed and hands crossed over their shoulders. Their feet are held in place by the researcher, and the individual is asked to perform trunk flexion. The number of repetitions completed within 30 seconds is recorded.
Modified Push-UpBaseline-6 weeks follow-upParticipants lie face down on an exercise mat with their knees flexed. They are asked to lift their head, torso, and hips off the ground, placing their hands on the floor and extending their elbows, so that they form a straight line. The number of complete repetitions the participant performs while maintaining this straight line within 30 seconds is recorded.
Core Endurance TestsBaseline-6 weeks follow-upCore endurance is determined by core endurance tests (right and left lateral bridge test, trunk extension test, trunk flexion test), as defined by McGgill, and the prone bridge test.

Secondary

MeasureTime frameDescription
30-Second Sit-Stand TestBaseline-6 weeks follow-upUsed to assess lower extremity muscle strength. The participant sits in the middle of a chair with no armrests, back support, and a seat height of 44 cm, with their arms crossed at chest level. Upon the command "Start," the participant is asked to fully stand up and sit down as quickly as possible without losing their balance for 30 seconds. The number of complete sit-ups and stands within 30 seconds is recorded as a score.
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)Baseline-6 weeks follow-upThe index is a validated, multidimensional, patient-reported assessment tool used to evaluate pain, stiffness, and physical function in patients with knee osteoarthritis. The index consists of three subcategories and a total of 24 items: pain (5 questions; 0-20 points), stiffness (2 questions; 0-8 points), and physical function (17 questions; 0-68 points). Each item is worth 0-4 points. The total score ranges from 0 to 96. In all subcategories and the total score, higher scores indicate worse health status, while lower scores indicate better health status.
Single Leg Balance TestBaseline-6 weeks follow-upParticipants were asked to stand on one leg on a hard surface, ensuring that the unsupported leg did not touch the other leg and without using external support. The procedure was repeated three times for each participant, and the highest value obtained was used in the statistical analysis phase. The timer was started the moment the participant lifted the supporting leg; it was stopped when the balance was lost, when the unsupported leg touched the ground, or when external support was applied. This test was repeated on both the right and left sides.

Countries

Turkey (Türkiye)

Contacts

CONTACTSelvin Balki, Associate Professor, Ph.D.
balkipt@gmail.com+90 346 4870000
CONTACTEda Yıldırım, PT
edaayldrm7@gmail.com+90 5056925334
STUDY_CHAIRSelvin Balki

Cumhuriyet University

PRINCIPAL_INVESTIGATOREda Yıldırım

Cumhuriyet University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 20, 2026