Postoperative Pain After Cesarean Section
Conditions
Brief summary
ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial
Interventions
DRUGThe TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)
the control group received only the same formula intravenous analgesia pump
Sponsors
Qing Yuan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Aged 20-40 years, in good general health * ASA physical status I-II * Singleton, term (37-41 weeks) pregnancy with normal fetal development * Planned for elective cesarean section, no labor
Exclusion criteria
* Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption) * Major organ dysfunction (heart, liver, kidney) or psychiatric history * Allergy to local anesthetics or any study drugs * Prior abdominal surgery or infection that may affect block efficacy * Coagulation disorders or current anticoagulant use * Refusal to participate or inability to comply with follow-up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively; | 5 months | VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity (coughing or turning) at 2, 6, 12, 24, and 48 hours postoperatively were recorded by anesthesiologists not involved in this study. |
Countries
China
Outcome results
None listed