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Coffee Increases Physical and Cognitive Performance Both in Men and Women

Habitual Caffeine Intake Affects the Ergogenicity of Dosing Regimens on Muscular Endurance But Not on Sprint and Cognitive Performance in Men and Women

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07474753
Enrollment
69
Registered
2026-03-16
Start date
2020-12-04
Completion date
2021-03-20
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dietary Supplement, Exercise

Brief summary

The impact of caffeine habituation on acute responses to different doses of caffeinated coffee has received minimal attention. This study aimed to investigate the effects of different doses of coffee on physical and cognitive performance in men and women with different levels of daily caffeine consumption. Sixty-nine (35 women) athletes participated in this study, attending 4 experimental visits in a double-blind, randomized, crossover fashion: decaffeinated coffee (PLA), 1.5 mg·kg-1 (LCOF), 3 mg·kg-1 (MCOF) and 6 mg·kg-1 of caffeine (HCOF) from coffee ingestion. Sixty min after coffee consumption, participants performed squat and bench press exercises (1 repetition maximum, 1RM), 60% of 1RM muscular endurance (ME), maximal sprinting, and cognitive performance (CP) was assessed. Participants were allocated into low (LGROUP), moderate (MGROUP), and high (HGROUP) caffeine consumption groups.

Interventions

DIETARY_SUPPLEMENTLow Dose Caffeine (LCOF)

Caffeinated versions of instant coffee were prepared in 600 ml hot water (approximately 65°C) and served in a mug. Participants ingested 0.12 g·kg-1 of decaffeinated coffee + 0.04 g·kg-1 of caffeinated coffee to achieve 1.5 mg·kg-1 of caffeine intake in LCOF 60-min before the experimental trial.

DIETARY_SUPPLEMENTModerate Dose Caffeine (MCOF)

Caffeinated versions of instant coffee were prepared in 600 ml hot water (approximately 65°C) and served in a mug. Participants ingested 0.08 g·kg-1 of decaffeinated coffee + 0.08 g·kg-1 of caffeinated coffee to achieve 3 mg·kg-1 of caffeine intake in MCOF 60-min before the experimental trial.

DIETARY_SUPPLEMENTHigh Dose Caffeine (HCOF)

Caffeinated versions of instant coffee were prepared in 600 ml hot water (approximately 65°C) and served in a mug. Participants ingested 0.16 g·kg-1 of caffeinated coffee to achieve 6 mg·kg-1 of caffeine intake in HCOF 60-min before the experimental trial.

DIETARY_SUPPLEMENTPlacebo (PLA)

Decaffeinated versions of instant coffee were prepared in 600 ml hot water (approximately 65°C) and served in a mug. Participants ingested 0.16 g·kg-1 of decaffeinated coffee in PLA 60-min before the experimental trial.

Sponsors

Northumbria University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)

Masking description

Supplements were allocated in a randomised order and double-blinding design was implemented by an independent technician who did not take part in the study. The randomisation and blinding were held until the end of the study.

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy individuals * Physically active individuals * Non-smokers * Age between 18 and 30 years * Free from respiratory insufficiency * Free from cardiovascular disease * Free from neuromuscular disorders * Free from musculoskeletal injury within the previous 6 months

Exclusion criteria

* Diagnosed cardiovascular disease * Neuromuscular disease * Current limb injury * History of limb injury requiring treatment within the previous 6 months * Chronic respiratory disease or treatment for chronic respiratory conditions

Design outcomes

Primary

MeasureTime frameDescription
Upper- and Lower-boy muscular endurance60 minutes after caffeine or placebo ingestion (during each experimental trial)Muscular endurance assessed during bench press and squat exercises using 60% of one-repetition maximum (1RM). Performance expressed as total weight lifted (kg).
Upper- and lower-body strenght60 minutes after caffeine or placebo ingestion (during each experimental trial)Maximal dynamic strength assessed using one-repetition maximum (1RM) tests in the squat and bench press exercises (kg).

Secondary

MeasureTime frameDescription
Sprint Performance60 minutes after caffeine or placebo ingestion (during each experimental trial)Peak power output and mean power output measured during a 15-second Wingate anaerobic test on a cycle ergometer (W/kg).
Cognitive performanceBaseline (before caffeine ingestion) and 60 minutes after caffeine or placebo ingestion.Reaction time (ms) and accuracy measured using a modified arrow flanker task.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026