ACS (Acute Coronary Syndrome), CKD, Coronary Angiography (CAG)
Conditions
Brief summary
This is the retrospective study regarding the association of invasive coronary angiography and time to renal replacement therapy initiation and mortality in patients with chronic kidney disease stage 4-5 who develop acute coronary syndrome.
Detailed description
Electronic medical records of adult patients admitted with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital, Thailand, were retrospectively reviewed. Eligible patients should have concurrent advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m² calculated by the 2021 CKD-EPI creatinine equation.
Interventions
PROCEDUREcoronary angiography
Standard coronary angiography
Sponsors
Chulalongkorn University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m² * Diagnosis with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital
Exclusion criteria
* Received maintenance dialysis or kidney transplantation before admission * Cardiogenic shock or cardiac arrest * Prior PCI or CABG within 12 months * Recently diagnosed with ACS within 2 months * Had a limited life expectancy due to non-cardiovascular disease * Pregnant.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Renal replacement therapy initiation | Until 31 December 2021 | Renal replacement therapy initiation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality | Until 31 Dec 2021 | All-cause mortality |
Outcome results
None listed