Gait Disorders
Conditions
Brief summary
This is a single-centre, cross-sectional observational study with adjunctive procedure for the healthy voluteers at IRCCS Ospedale San Raffaele's Rehabilitation Department. Patients (n=50): use of inertial measurement units (IMU) and electromyographic (EMG) data routinely acquired during their standard clinical gait-rehabilitation sessions (no protocol changes; purely observational, data extracted from treatments). Healthy volunteers (n=50): age- and sex-matched volunteers who complete three 18 meters gait sessions with IMUs on trunk, thighs, shanks and feet and surface EMG on gluteus, quadriceps, hamstrings, tibialis anterior, and gastrocnemius. Healthy volunteers will be enrolled from hospital personnel, family members of the patients in visit at San Raffaele Hospital. Data & Analysis: Kinematic (range of motion - ROM, step timing, walking speed) and EMG (activation amplitude/timing) parameters will be extracted. Between-group comparisons will employ t-tests/analysis of variance - ANOVA - (or non-parametric equivalents).
Interventions
OTHERGait assessment
Gait assessment with wearable sensors
Sponsors
IRCCS San Raffaele
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Hospitalized at the Department of Rehabilitation and Functional Recovery of IRCCS Ospedale San Raffaele - Milan (during the hospitalization period) * Ability to understand and sign informed consent * ≥ 18 years ≤80 years * Male and female * Presence of clinically diagnosed gait impairments * No skin conditions or allergies preventing sensor application
Exclusion criteria
* Cognitive impairment interfering with task comprehension * Cardiorespiratory instability or other contraindications to walking assessment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean differences in joint range of motion expressed in degrees of movement (hip, knee, ankle) measured by sensors (Inertial Measurement Units) between patients and healthy volunteers | Baseline (single time point) | Joint range of motion of the hip, knee, and ankle measured using inertial measurement units (IMUs) and expressed in degrees (°). The outcome represents the mean difference in joint range of motion between patients and healthy volunteers; higher values indicate greater angular excursion of the joint. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Average of the normalized enveloped of surface electromyography signals | Baseline (single time point) | Surface electromyography (sEMG) signals processed to obtain the signal envelope and then normalized. The outcome measure represents the average normalized sEMG envelope amplitude, providing an index of muscle activation level over the analyzed task; higher values indicate greater muscle activation relative to the normalization reference. |
Countries
Italy
Contacts
CONTACTSandro Iannaccone, Neurologist
Outcome results
None listed