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Incidence and Risk Factors of Intraoperative Hypothermia in Adult Patients After Protocol Implementation

Incidence and Risk Factors of Intraoperative Hypothermia in Adult Patients at Siriraj Hospital: An Evaluation After Implementation Management Protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07470801
Enrollment
361
Registered
2026-03-13
Start date
2026-02-27
Completion date
2027-06-01
Last updated
2026-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothermia Following Anesthesia

Keywords

Hypothermia, Intraoperative hypothermia

Brief summary

Inadvertent intraoperative hypothermia is one of the most common complications in patients undergoing anesthesia. This condition is strongly associated with several adverse clinical. At Siriraj Hospital, a previous study revealed a high incidence rate of 74.4%, with only 16.3% of patients receiving intraoperative temperature monitoring. In response to these findings, Siriraj Hospital implemented a perioperative temperature management guideline in July 2024. However, it remains to be evaluated whether the implementation of this protocol has led to a meaningful change in clinical practice. The primary concern is whether the adherence to temperature monitoring for surgeries exceeding one hour has improved from the historical rate of 16.3%, and subsequently, whether this has resulted in a decreased incidence of hypothermia.

Detailed description

Inadvertent intraoperative hypothermia, defined as a core body temperature below 36 C, is one of the most common complications in patients undergoing anesthesia. This condition is strongly associated with several adverse clinical outcomes, including increased risk for surgical site infections, delayed wound healing, prolonged recovery and hospitalization, coagulopathy, and increased requirements for blood transfusion. Many risk factors are associated with inadvertent intraoperative hypothermia including: high ASA physical status, age \>65-year, general anesthesia combined with neuraxial anesthesia, longer anesthesia duration, emergency major surgery, intraoperative blood loss and intravenous fluid volume received. Despite the existence of international recommendations from organizations like the American Society of Anesthesiologists (ASA) and the National Institute for Health and Care Excellence (NICE)-which recommend interventions including active warming, using warm irrigation fluid, and continuous temperature monitoring to minimize the risk of intraoperative hypothermia, hypothermia remains prevalent in many settings. At Siriraj Hospital, a previous study revealed a high incidence rate of 74.4%, with only 16.3% of patients receiving intraoperative temperature monitoring. In response to these findings, Siriraj Hospital implemented a standardized perioperative temperature management guideline (protocol) in July 2024. This protocol recommends pre-warming and active warming strategies to mitigate extrinsic risk factors, such as low operating room temperatures and the administration of cold intravenous fluids. However, it remains to be evaluated whether the implementation of this protocol has led to a meaningful change in clinical practice. The primary concern is whether the adherence to temperature monitoring for surgeries exceeding one hour has improved from the historical rate of 16.3%, and subsequently, whether this has resulted in a decreased incidence of hypothermia. Furthermore, intrinsic patient factors-such as age, Body Mass Index (BMI), and surgical complexity-continue to be potential variables that the protocol alone may not fully address. To date, the real-world impact of this specific protocol on reducing hypothermia has not been formally evaluated. Therefore, this study is essential to evaluate the effectiveness of the Siriraj temperature management protocol. The findings will not only determine the current intraoperative monitoring rate and the incidence of hypothermia but also identify significant intrinsic risk factors that persist despite standardized care. This information will be vital for further quality improvement and ensuring patient safety in the perioperative setting at Siriraj Hospital.

Interventions

None listed

Sponsors

Siriraj Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adult patients undergoing non-cardiac surgery under anesthesia service Patients undergoing surgery after the implementation of the temperature management protocol (from July 2024 onwards)

Exclusion criteria

* Procedures performed under local anesthesia or monitored anesthetic care Anesthesia duration of less than 60 minutes

Design outcomes

Primary

MeasureTime frameDescription
Incidence of intraoperative hypothermiaNovember to December 2025Presence of hypothermia defined as core temperature less than 36 C

Secondary

MeasureTime frameDescription
The proportion of patients who received intraoperative temperature monitoringNovember to December 2025Percentage of patients receiving intraoperative temperature monitoring
Time to onset hypothermia, duration of hypothermia, lowest temperatureNovember to December 2025
Incidence of postoperative hypothermiaNovember to December 2025Percentage of patients having core temperature less than 36 C at the arrival of the recovery unit
Recovery timeNovember to December 2025Time from finished operation to patient transfer recorded in minutes
Blood lossNovember to December 2025Amount of blood loss recorded in mL
Length of post-anesthesia care unit stayNovember to December 2025The amount of time the patient spent in the recovery unit was recorded in minutes.
Length of hospital stayNovember to December 2025The total admission days recorded in days
Blood transfusionNovember to December 2025Amount of blood transfusion given intraoperatively in mL

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 14, 2026