Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy.

Comparison Of Postoperative Analgesia In Landmark Guided Erector Spinae Plane Block And Subcostal Transversus Abdominis Plane Block In Laparoscopic Cholecystectomy; A Randomized Controlled Trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07469410

Enrollment

Registered

2026-03-13

Start date

2025-06-01

Completion date

2025-11-15

Last updated

2026-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Analgesia

Keywords

ESPB, STAP, landmark-guided blocl, laparoscopic cholecystectomy, post operative analgesia

Brief summary

Postoperative pain after laparoscopic cholecystectomy remains clinically relevant. This double-blinded randomized controlled trial compares the analgesic efficacy of landmark-guided Erector Spinae Plane Block (ESPB) and subcostal transversus abdominis plane (STAP) block in 60 adult patients. Postoperative pain will be evaluated using the Visual Analogue Scale at multiple time points, along with rescue analgesic requirements and time to first analgesic request, to assess the effectiveness of these techniques in resource-limited settings.

Interventions

DRUGLandmark guided Erector Spinae Block

Patients will receive a landmark-guided Erector Spinae Plane Block on the right side at T9 level with 30 mL of 0.25% ropivacaine after induction of general anesthesia.

DRUGLandmark guided Transversus Abdominis Plane Block

Patients will receive a landmark-guided Subcostal Transversus Abdominis Plane Block on the right side with 30 mL of 0.25% ropivacaine after induction of general anesthesia.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients are both men and women. * Patients aged 18 to 65. * Patients are scheduled for a laparoscopic cholecystectomy. * Patients with ASA Physical Status I or II. Finally, III. * Give consent.

Exclusion criteria

* Hypersensitivity to local anesthesia. * Infection at the block site. * Coagulation disorders. * BMI above 40kg/m2. * Patients with pregnancy. * Converted to open surgery. * Drain placement. * Neurological or psychiatric disorders that impair cooperation. * Patients are unwilling to cooperate.

Design outcomes

Primary

Measure	Time frame	Description
VAS score	From arrival in the post-anesthesia care unit (PACU) through 24 hours postoperatively, assessed at 30 minutes in PACU, and at 6 hours, 12 hours, and 24 hours after surgery.	Postoperative pain intensity measured using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 to 10, where 0 = no pain and 10 = worst imaginable pain. Higher scores indicate worse pain.

Secondary

Measure	Time frame	Description
need for rescue analgesia and time for first analgesic request.	From completion of surgery through 24 hours postoperatively.	Proportion of patients requiring rescue analgesia during the postoperative period.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 14, 2026