Chronic Knee Osteoarthritis, Shock Wave, Traditional Physical Therapy
Conditions
Brief summary
This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.
Detailed description
Knee osteoarthritis (KOA) is a highly prevalent chronic degenerative joint disease characterized by progressive cartilage loss, chronic pain, stiffness, functional disability, and reduced quality of life in adults, particularly the elderly. Extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive physical modality that delivers acoustic pressure waves to musculoskeletal tissues, stimulating biological responses such as enhanced microcirculation, anti-inflammatory cytokine modulation, neovascularization, cartilage and bone repair processes, and decreased pain transmission.
Interventions
OTHERExtracorporeal shock wave therapy
Patients will receive extracorporeal shock wave therapy.
Patients will undergo a structured exercise therapy program.
Sponsors
German International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults ≥ 40 years with clinical and radiographic diagnosis of chronic knee osteoarthritis (KOA) (Kellgren-Lawrence grade II-III). * Both sexes. * Persistent knee pain ≥ 3 months. * Ability to provide consent and participate in interventions.
Exclusion criteria
* Prior knee surgery within last 6 months. * Intra-articular injections in the last 3 months. * Systemic inflammatory arthritis or other neurological conditions affecting gait.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in pain intensity | 5-week after intervention | Change in pain intensity will be assessed using the Visual Analogue Scale (VAS) which is a 10-cm horizontal line used to measure pain intensity, ranging from (0) "no pain" to (10) "worst imaginable pain". |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stiffness assessment | 5-week after intervention | Stiffness will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). WOMAC will be recorded at baseline, at the end of the intervention period, and during follow-up. Higher scores indicate greater symptom severity. |
| Assessment of physical function | 5-week after intervention | Physical function will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). WOMAC will be recorded at baseline, at the end of the intervention period, and during follow-up. Higher scores indicate greater symptom severity. |
| Knee range of motion | 5-week after intervention | Knee range of motion (ROM) will be assessed. |
| Incidence of adverse events | 5-week after intervention | Incidence of adverse events will be recorded. |
Countries
Egypt
Contacts
CONTACTMagdy M Shabana, MD
Outcome results
None listed