Cognitive Control, Memory
Conditions
Brief summary
This study aims to clarify relations between brain oscillations and two cognitive functions: cognitive control and memory.
Interventions
DEVICESham device
Intervention which uses an inactive form of stimulation via electrodes on the scalp.
DEVICESTARSTIM Device in-phase
Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of in-phase theta (\~3.5 to \~7.5 Hz) via electrodes on the scalp.
DEVICESTARSTIM Device anti-phase
Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of anti-phase stimulation via electrodes on the scalp.
Sponsors
Florida International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* 18 years and older * Fluent in English * Normal or corrected-to-normal vision * Willing to be photographed
Exclusion criteria
* Must not have ever had an injury to the head that's caused you to be knocked out for a period of time (e.g., from a fall, blow to the head, road traffic accident). * Must not have an uncorrected vision or physical disability that interferes with your ability to see stimuli presented briefly on a computer screen or click a mouse button rapidly. * Must not have a history of epilepsy, convulsions, or seizures (except childhood febrile seizures). * Must not have a history of fainting or syncope. * For female participants, they must not be pregnant and/or must not think they might be pregnant. * Must not have skin problems like eczema, dermatitis, or open wounds on the scalp. * Must not have had prior brain surgery. * Must not have any metal located in the head/neck (except for dental work i.e., braces, permanent retainers, etc.) * Must not have any devices or other implants located in/near their head. This includes cochlear implants and aneurysm clips, cardiac pacemaker, or any other implanted electronic device. * Must not have a current (active) alcohol or substance use disorder, must have no recent history of withdrawal symptoms, and must be able to safely abstain from alcohol and non-prescribed/illicit drugs for at least 24 hours before the session. * Must not have any alcohol on the day of the session, must limit alcohol consumption to no more than 2 drinks (if legally permitted) in the prior 24 hours, and must not use any non-prescribed or illicit drugs in the 24 hours before the session. * Must not be sick with a fever, sleep-deprived, or feel dizzy, unwell, or intoxicated. * Must also have eaten and had fluids but not have consumed more caffeine than they typically consume. * Must not be taking anticonvulsant/anti-epileptic drugs or have ever taken them within their lifetime. * Must not be taking benzodiazepines or have taken them within the past 3 months. * Must not have had a recent change (start, stop, dose change) for any psychiatric/psychotropic medications within the past 3 months. * Must not be taking Bupropion (Wellbutrin, Zyban), Tricyclic antidepressants (e.g., amitriptyline, imipramine, clomipramine, etc.), Antipsychotics (clozapine; chlorpromazine, haloperidol, etc.), or Tramadol or have taken them within the past 3 months. * Must not have experienced cardiac problems, fibrillation, or have taken medications associated with cardiac conditions within the past 3 months. * Must not meet the diagnostic threshold for Autism Spectrum Disorder, Intellectual Disability, or Psychotic Disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Difference Between Incidental Memory of Faces on Error versus Correct Trials from Baseline to Post Brain Stimulation | Baseline through study visit completion, a maximum of 3 hours | The hit rate for faces that appeared on error trials minus the hit rate for faces that appeared on correct trials. |
Countries
United States
Outcome results
None listed