The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients

Rapid Shallow Index as Successfully Predictor of Outcome of Extubating

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07467265

Enrollment

Registered

2026-03-12

Start date

2026-03-01

Completion date

2026-09-01

Last updated

2026-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Failure of Extubation, Ventilated Patient in Intensive Care

Keywords

RSBI.VAP.success of extubation

Brief summary

Early extubation in ICU patients is crucial for reducing complications of prolonged ventilation, including morbidity and mortality. The Rapid Shallow Breathing Index (RSBI) is a widely used predictor for weaning patients from mechanical ventilation. This study aims to determine the predictive value of RSBI measurements for extubation success in mechanically ventilated ICU patients

Detailed description

The extubation decision is a combined clinical judgment based on a passing Spontaneous Breathing Trial (SBT) and a Rapid Shallow Breathing Index (RSBI) value ≤ 105 breaths/min/L.combination of criteria (SBT + RSBI threshold) This approach is recommended to improve predictive accuracy, as neither SBT nor RSBI alone is perfectly reliable.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

22 Years to No maximum

Healthy volunteers

Inclusion criteria

* • Adults \> 22 years. * Mechanically ventilated patients meeting extubation readiness: * FiO₂ ≤ 0.4, PEEP ≤ 8 cmH₂O, PaO₂/FiO₂ ≥ 200 mmHg. * Respiratory rate ≤ 35 breaths/min, pH \> 7.30. * Hemodynamic stability (HR ≤ 120 bpm, SBP 90-160 mmHg). * Glasgow Coma Scale \>10, adequate cough reflex. * Includes postoperative, elective/emergency reintubation, and tracheostomized patients.

Exclusion criteria

* Age \<22 years. * Refusal of informed consent. * Altered mental status (e.g., traumatic brain injury). * Hemodynamic instability or deep sedation (RASS ≤ -2).

Design outcomes

Primary

Measure	Time frame	Description
Extubation success (no reintubation/adjuvant support within 48h).	48 hour	no reintubation or adjuvant oxygen therapy

Countries

Egypt

Contacts

CONTACTSarah hamdy Elghareeb, MD

sarahhamdy@med.asu.edu.eg+201012434690

Outcome results