Cardiac Conduction Disturbance
Conditions
Brief summary
During pacemaker implantation, the atrial lead is commonly positioned in the right atrium. However, this pacing location can be problematic because it may disrupt physiological atrial activation, leading to atrial dyssynchrony. Such dyssynchrony has been associated with an increased risk of atrial fibrillation and its related complications. To mitigate atrial dyssynchrony, pacing of the Bachmann's bundle region has emerged as an alternative strategy. Bachmann's bundle is the principal interatrial conduction pathway, and pacing at this site may help preserve physiological atrial activation. Several studies have suggested that pacing in this region can significantly reduce the incidence of new-onset atrial fibrillation and heart failure in selected populations. To date, however, robust data from large cohorts regarding the feasibility of Bachmann's bundle area pacing and the factors associated with successful implantation remain limited. To address this gap, we established the Bachstim cohort study, aimed at determining the success rate of Bachmann's bundle area pacing and identifying the clinical and procedural factors associated with its feasibility.
Interventions
DEVICEBachmann's area pacing
In this study, the atrial lead will be targeted to the Bachmann's bundle area, rather than the conventional right atrial appendage pacing site.
Sponsors
University Hospital, Caen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Cardiac pacemaker with atrial lead indication
Exclusion criteria
* patients \< 18 years old * pregnancy of breast feeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success of Bachmann's area pacing | 10 minutes | Successful Bachmann's bundle area pacing is defined by a reduction of the paced P-wave duration by at least 30 ms when the spontaneous P-wave duration exceeds 120 ms, or by a reduction of the paced P-wave duration by at least 10 ms when the spontaneous P-wave duration is ≤120 ms. |
Secondary
| Measure | Time frame |
|---|---|
| Success of Bachmann's area pacing after 3 months follow-up | 3 months |
| Success of Bachmann's area pacing after12 months follow-up | 12 months |
| AF burden after 12 months follow-up | 12 months follow-up |
Countries
France
Contacts
CONTACTJonaz FONT, MD, MSc
Outcome results
None listed