A Novel Approach in the Evaluation of Breast Masses With Doppler US

A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07465523

Enrollment

Registered

2026-03-12

Start date

2026-03-04

Completion date

2026-05-19

Last updated

2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Breast Neoplasm, Breast Neoplasm Female, Doppler Ultrasound Diagnosis, Malign Breast Neoplasm

Keywords

Breast Mass, Doppler Ultrasound, B-Mode Ultrasound, Resistive Index

Brief summary

In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant masses will be evaluated.

Detailed description

The aim of this study is to reveal the role of differences in the resistive index of masses and surrounding tissue in distinguishing between benign and malignant masses using a new approach in the evaluation of breast masses with Doppler ultrasound. The minimum, maximum, and average RI values obtained from the mass and healthy breast tissue will be recorded. The relative RI value difference will be calculated from the RI values of the mass and healthy tissue. Based on the pathology results, the cases will be divided into two groups: benign and malignant. The threshold values of these values in malignant and benign masses will be determined and compared. Additionally, vascular index values in breast masses will be calculated and compared using the relatively new Doppler Microvascular Flow method.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Those with solid breast masses * Female patients * Those with pathology results

Exclusion criteria

* Hypovascular masses * Cystic breast masses * Cases with mastitis

Design outcomes

Primary

Measure	Time frame	Description
A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation	3-4 months	ROC curve analysis will be applied for the diagnostic performance of relative RI change in benign and malignant lesions.

Countries

Turkey (Türkiye)

Contacts

CONTACTAhmet Yeşildağ, Prof.Dr

ahmetysd@hotmail.com+905057728297

CONTACTGökçe Merve Arman, Dr.

gmerveturgut@gmail.com+905058734762

STUDY_DIRECTORAhmet Yeşildağ, Prof.Dr.

Karamanoğlu Mehmetbey Universty

Outcome results