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IJV Catheterization and Intracranial Pressure Via ONSD

Evaluation of the Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Using Optic Nerve Sheath Diameter in Intubated Patients in the Intensive Care Unit

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07465419
Enrollment
50
Registered
2026-03-11
Start date
2026-02-01
Completion date
2026-06-01
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial Pressure Measurement, Measurement of Optic Nerve Sheath Diameter

Brief summary

The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter

Detailed description

Before central venous catheter insertion, the baseline ONSD value will be determined by measuring the optic nerve sheath diameter in the supine and Trendelenburg positions (15 degrees head down). Immediately after central venous catheter insertion, the measurement will be taken while the patient is still in the Trendelenburg position. The measurement will be repeated at 5, 15, and 30 minutes after the patient is placed in the supine position. Transorbital optic nerve sheath diameter measurements will be performed using the linear probe of the ultrasound device routinely used in our clinic. The ultrasound linear probe will be gently placed on the eyelid over the closed eye, ensuring no pressure is applied to the patient's eye. The length of the line representing the optic nerve sheath diameter, which intersects the line drawn 3 mm downwards from the lower edge of the eyeball seen on the ultrasound, will be measured and recorded. The optic nerve sheath diameter will be measured transorbitally vertically once from each eye during the first measurement, and the average will be taken.

Interventions

Internal jugular vein catheterization

Sponsors

Cumhuriyet University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit.

Exclusion criteria

* patients with intracranial tumors * patients with acute traumatic brain injury * patients diagnosed with acute or chronic eye diseases * hypercarbic patients * Patients receiving inotropic support * patients using medications that affect intraocular pressure

Design outcomes

Primary

MeasureTime frameDescription
Optic nerve sheath diameterPrior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterizationOptic nerve sheath diameter will be measured via ultrasound prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 23, 2026