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Stabilization vs Corrective Exercise in PFP

Functional Stabilization Training VS Comprehensive Corrective Exercises on Lower Limb Kinematics in Patellofemoral Pain and Dynamic Knee Valgus

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07465380
Enrollment
60
Registered
2026-03-11
Start date
2026-04-01
Completion date
2027-04-01
Last updated
2026-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral Pain Syndrome

Keywords

Exercise Therapy, Genu Valgum

Brief summary

The purpose of this study is to investigate the effects of a Functional Stabilization training program (FST) and a comprehensive corrective exercise program in PF pain and DKV.

Detailed description

PF pain impairs performance and quality of life and can predispose individuals to early PF osteoarthritis and Dynamic knee valgus has been identified as a modifiable risk factor for PF pain and serious knee injury . Current rehabilitation strategies show mixed results. Solo hip strengthening programs may not correct Dynamic knee valgus. While both Functional Stabilization training (FST) and comprehensive corrective programs (CCEP) show potential benefits, direct comparisons are lacking. The FST suggested superior outcomes with functional training, but it did not specifically target DKV. Conversely, the CCEP demonstrated kinematic improvements, but included asymptomatic participants and lacked patient reported outcomes. By directly comparing Functional Stabilization training (FST) with the CCEP, this study aims to provide clinicians with evidence based guidance on the most effective exercise strategy for improving lower limb kinematics and reducing pain. The findings could inform best practice guidelines and enhance outcomes.

Interventions

BEHAVIORALStandard Care Exercise Program (SC)

Supervised standard care exercise therapy for patellofemoral pain, delivered 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session.

BEHAVIORALFunctional Stabilization Training (FST)

Supervised functional stabilization/neuromuscular exercise program focusing on lower-limb alignment and movement control. 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session, progressive difficulty/load

Supervised comprehensive corrective exercise program targeting flexibility, strength, and neuromuscular control across the kinetic chain to address dynamic knee valgus. 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session, phase-based progression

Sponsors

Ahram Canadian University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* Patellofemoral pain lasting \> 6 weeks * Demonstrates dynamic knee valgus during single-leg squat (FPPA ≥ 10°). * Arabic Kujala Patellofemoral Scale (KPS) score \< 80. * Age 18-35 years

Exclusion criteria

* Previous knee surgery; ligament/meniscus injury; or lower-limb fractures * Neurologic disorders. * Systemic inflammatory disease * Pregnancy.

Design outcomes

Primary

MeasureTime frameDescription
Peak Knee Abduction (Valgus) Angle (3D motion analysis)Baseline and 8 weeksChange in peak knee abduction (valgus) angle of the stance limb measured using a 3D motion capture system (Vicon) during functional tasks (single-leg squat and drop/vertical jump landing). Lower values indicate reduced dynamic knee valgus.
Hip and Pelvis Kinematics (3D motion analysis)Baseline and 8 weeksChange in peak hip adduction, peak hip internal rotation, contralateral pelvic drop, and trunk lateral lean during the functional tasks measured by 3D motion capture.

Secondary

MeasureTime frameDescription
Kujala Patellofemoral Scale (KPS)Baseline and 8 weeksChange in patient-reported knee function using the Arabic Kujala Patellofemoral Scale (0-100)

Contacts

CONTACTAhmed Alshab, PhD Cand
ahmed.s.alshabb@gmail.com+201008816911
CONTACTEnas Fawzy, PhD
enas.fawzy@pt.cu.edu.eg

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026