Cohort Study of Chronic Liver Disease Complicated by Sepsis

Use of Antimicrobial Drugs in Severe Infections and Epidemiological Study of Populations With Severe Infections

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07465003

Enrollment

1600

Registered

2026-03-11

Start date

2026-02-25

Completion date

2028-06-01

Last updated

2026-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis, Sepsis

Brief summary

Study population: Patients with liver cirrhosis complicated by sepsis Observation indicators: Fluid resuscitation strategy, early dynamic indicators such as MAP Observation endpoint: 28-day all-cause mortality Study design: Retrospective cohort study

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Clinically or pathologically diagnosed with cirrhosis; * meets the Sepsis-3 diagnostic criteria.

Exclusion criteria

* Combined organ transplantation, active malignant tumors; * Pregnant or breastfeeding women; * Long-term use of immunosuppressants (non-steroidal); * Death or voluntary discharge within 24 hours of admission; * Incomplete data.

Design outcomes

Primary

Measure	Time frame
28-day all-cause mortality in cirrhosis with sepsis	Baseline and 28 days.

Contacts

CONTACTLi ShiYing Deputy Chief Physician of the Department of Infectious Disease, Ph.D

302946@hospital.cqmu.edu.cn0086+18623322462

Outcome results