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Effects of Music Therapy on Anxiety and Distress Levels During Radionuclide Treatment in Prostate Cancer Patients

Effects of Music Therapy on Anxiety and Distress Levels During Radionuclide Treatment in Prostate Cancer Patients

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07464964
Acronym
MUSIC-PRT
Enrollment
60
Registered
2026-03-11
Start date
2023-09-01
Completion date
2025-09-30
Last updated
2026-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Music Therapy, Prostate Cancer (Diagnosis), Psychological Distress

Keywords

Music Therapy, Radionuclide Therapy, Prostate Cancer, Anxiety, Distress

Brief summary

This interventional study aimed to evaluate the effects of music therapy on anxiety and distress levels in patients with prostate cancer undergoing radionuclide therapy. A total of 60 patients who met the eligibility criteria were included in the study. Participants were assigned to either an intervention group or a control group. Patients in the intervention group listened to music through headphones during the radionuclide treatment session, while patients in the control group received standard care without a music intervention. Music selections included various types of non-verbal music such as classical music, Turkish classical music, and other instrumental genres. Participants were allowed to select their preferred music from a predefined list. Psychological distress and anxiety levels were assessed using the Distress Thermometer and the Hospital Anxiety and Depression Scale. Measurements were obtained before the treatment session and again after completion of the radionuclide therapy. The study evaluated whether listening to music during treatment could reduce anxiety and distress levels in patients receiving radionuclide therapy for prostate cancer.

Detailed description

ntervention and Implementation Eligible patients undergoing radionuclide therapy in the nuclear medicine unit were evaluated for participation in the study. After receiving information about the study and providing written informed consent, participants were allocated to either the intervention group or the control group. The first eligible patient was assigned to the intervention group and the second patient to the control group. This sequence was continued until a total of 60 patients were included in the study. Patients in the intervention group listened to music during radionuclide therapy, while patients in the control group received standard care without music intervention. Music Intervention The music intervention consisted of listening to instrumental, non-verbal music through headphones during radionuclide therapy. Participants were allowed to choose their preferred music from a categorized list including classical music, Turkish classical music, Turkish makam music (Uşşak, Rast, Zirgüle, Hüseyni), jazz music, and other instrumental music genres. Music playlists were prepared according to patient preferences prior to the treatment session. Participants were instructed on how to use the headphones and how to adjust the volume to a comfortable level. The music was played continuously during the treatment session for approximately 20-40 minutes. Individual music preference was considered an important factor in the intervention. Therefore, patients were allowed to select music genres that they felt most comfortable with. Only instrumental or lyric-free music was used to minimize distraction and promote relaxation. Intervention Protocol Intervention Group Before radionuclide therapy, participants completed a questionnaire regarding sociodemographic and disease-related characteristics. Baseline levels of anxiety and distress were measured using the Hospital Anxiety and Depression Scale (HADS) and the Distress Thermometer. During radionuclide therapy, patients listened to their selected music through headphones for approximately 20-40 minutes. At the end of the treatment session, the Distress Thermometer and HADS were administered again to assess post-treatment anxiety and distress levels. Control Group Patients in the control group received standard care without music intervention. Before radionuclide therapy, participants completed the sociodemographic and disease-related questionnaire as well as baseline assessments using the Hospital Anxiety and Depression Scale and the Distress Thermometer. At the end of the treatment session, the same assessment tools were administered again to evaluate post-treatment anxiety and distress levels.

Interventions

BEHAVIORALMusic Therapy

Listening to instrumental music through headphones during radionuclide therapy for approximately 20-40 minutes based on patient preference.

Sponsors

Dokuz Eylul University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

Participants were assigned to either an intervention group or a control group using a sequential allocation method. Patients in the intervention group listened to music during radionuclide therapy, while patients in the control group received standard care without music intervention. Anxiety and distress levels were measured before and after the treatment session.

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Male patients aged 18 years or older Patients diagnosed with prostate cancer Patients receiving the first course of radionuclide therapy Patients without hearing or speech problems Patients not receiving psychiatric treatment (not using anti-anxiety or antidepressant medications) Patients who are not in the terminal stage of the disease Patients who have and are able to use a smartphone with an Android or iOS operating system Patients who voluntarily agreed to participate in the study and provided written informed consent

Design outcomes

Primary

MeasureTime frameDescription
Change in Anxiety LevelBaseline (before radionuclide therapy) and immediately after completion of each radionuclide therapy session, assessed over three treatment cyclesAnxiety levels were assessed using the Hospital Anxiety and Depression Scale (HADS). The scale was administered before radionuclide therapy and again after completion of the treatment session to evaluate changes in anxiety levels between the intervention and control groups.

Secondary

MeasureTime frameDescription
Change in Psychological Distress LevelBaseline (before radionuclide therapy) and immediately after completion of each radionuclide therapy session, assessed over three treatment cyclesDistress levels will be assessed using the Distress Thermometer, which ranges from 0 (no distress) to 10 (extreme distress). Higher scores indicate greater psychological distress.

Countries

Turkey (Türkiye)

Contacts

STUDY_DIRECTOREzgi Karadağ, Prof

Dokuz Eylul University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026