Halitosis, Periodontitis, Type 2 Diabetes
Conditions
Keywords
Halitosis, periodontitis, lasers, Photodynamic Therapy
Brief summary
The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in reducing halitosis in individuals with periodontal disease and type 2 diabetes mellitus. The main question it aims to answer is: aPDT treatment is more effective in treating halitosis? aPDT treatment is more effective in periodontitis? Researchers will compare aPDT treatment to conventional treatment (scaling and root planning and tongue scraper) to see if aPDT has additional effects in reducing halitosis and improving periodontal health. * Participants will be asked to visit the clinic once a week for exam and treatment during 1 month. * After active treatment they will be asked to come to maintenance and control visits once a month until 6 months.
Interventions
PROCEDUREScaling and root planing
Mechanical removal of biofilm in periodontal pockets and tongue
Antimicrobial photodynamic therapy in periodontal pockets and tongue
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Masking description
Simulation of laser treatment
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with type 2 diabetes mellitus according to the 2019 WHO criteria * Stage 3 or 4 periodontitis * No periodontal treatment in the previous 12 months * a minimum of 20 remaining teeth.
Exclusion criteria
* Smokers * Alcohol-dependent individuals * Pregnant or lactating women * Patients with renal disorders * Patients using medications that affect the periodontium
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Halitosis | From enrollment to the end of treatment at 6 months | Measurement of oral volatile compounds by gas chromatography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth | From enrollment to the end of treatment at 6 months | Measurement in milimeters of the periodontal pocket |
| Clinical Attachment level | From enrollment to the end of treatment at 6 months | Measuremet in milimeters from cementoenamel junction to bottom of the pocket |
Countries
Brazil
Contacts
CONTACTCarla A. Damante, PhD
Outcome results
None listed