Parodontopathy
Conditions
Brief summary
Objective: To evaluate patient satisfaction, postoperative pain, inflammatory re-sponse, and analgesic consumption following All-on-Four implant surgery performed under analgosedation. Methods: This prospective clinical study will include 30 adult patients classified as ASA physical status I-II who were scheduled for elective full-arch rehabilitation using the All-on-Four protocol under analgosedation. Patients with contraindications to sedation, cognitive impairment, or emergency indications will be excluded. Postoperative pain and swelling will be assessed using a visual analogue scale (VAS) up to 72 hours. Real analgesic consumption will be recorded during the first three postoperative days. Systemic inflammatory response will be evaluated by serum C-reactive protein (CRP) levels measured preoperatively and on postoperative day 3. Patient experience with anesthetic management will be assessed using a structured questionnaire.
Interventions
PROCEDUREFull arch rehabilitation with four dental implants
The elective full-arch rehabilitation using the All-on-Four protocol under analgosedation
Sponsors
University of Zagreb
St. Catherine Specialty Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients scheduled for elective full-arch implant rehabilitation * ASA physical status I or II * Ability to understand the study procedures and provide written informed consent
Exclusion criteria
* Emergency dental or surgical intervention * Pregnancy * Patients with cognitive impairment or psychiatric conditions affecting reliable outcome reporting * Patients with contraindications to analgo-sedation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient Reported postoperative pain andswelling | "From enrollment to the end of treatment at 3 days" | The primary outcome measures included patient-reported postoperative pain and swelling, analgesic use and systemic inflammatory response. Postoperative pain intensity and swelling were assessed using a 10-point Visual Analogue Scale (VAS), where 0 indicated the absence of symptoms and 10 indicated the maximum perceived severity. Assessments were performed preoperatively and at 2, 6, 12, 24, 48, and 72 hours postoperatively. |
| Rescue analgesic consumption | From surgery up to 3rd postoperative day | Rescue analgesic consumption was recorded for each patient during the first three postoperative days and quantified based on the total number of tablets consumed and daily dose. Analgesic intake was used as an indirect indicator of postoperative discomfort. |
| The systemic inflammatory response | "From enrollment to the end of treatment at 3 days" | To evaluate the systemic inflammatory response, serum C-reactive protein (CRP) levels were measured preoperatively and on postoperative day 3 using standard laboratory procedures. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient experience with analgosedation | "From enrollment to the end of treatment at 3 days" | All patients were asked to complete a structured questionnaire assessing their experience with anesthetic management. The questionnaire collected demographic data and medical history, and included items related to previous exposure to analgosedation, attitudes toward different anesthesia modalities, perioperative anxiety, adequacy of preoperative information, patient involvement in anesthesia decision-making, and overall satisfaction with the anesthetic care. In addition, patients were asked to report intraoperative and early postoperative discomfort, adverse sensations following emergence from analgosedation, and their willingness to undergo the same anesthesia protocol in the future |
Countries
Croatia
Outcome results
None listed