Upper Gastrointestinal Cancer, Upper Gastrointestinal Precancerous Conditions, Upper Gastrointestinal Precancerous Lesions
Conditions
Keywords
image database, upper gastrointestinal cancer
Brief summary
The study is designed to collect magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, CT images, and histopathology results to establish a database for early upper gastrointestinal cancer, precancerous lesions, and precancerous conditions.
Detailed description
Images of MCE for UGIC are scarce, limiting the development of corresponding AI diagnostic model. We aim to create an image database with MCE images, EGD images, CT images, and histopathology results, in patients treated by ESD for early upper gastrointestinal cancer, or biopsy for precancerous lesions, and precancerous conditions, so as to facilitate image-based deep learning studies.
Interventions
DIAGNOSTIC_TESTmagnetically-controlled capsule endoscopy, esophagogastroduodenoscopy, CT scan
Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images for early upper gastrointestinal cancer, precancerous lesions, and precancerous conditions
PROCEDUREESD, biopsy
ESD or biopsy for histopathology results
Sponsors
Changhai Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Male or female participants aged ≥ 18 years 2. Patients with early upper gastrointestinal cancer referred for endoscopic submucosal dissection (ESD), or patients with upper gastrointestinal precancerous lesions or precancerous conditions referred for biopsy by esophagogastroduodenoscopy (EGD) 3. Participants who are willing and able to participate in this study, complete all required examinations and follow-up visits, and who have provided written informed consent
Exclusion criteria
1. Patients who are not eligible for surgery or who refuse any abdominal surgery in case of capsule retention and endoscopic retrieval failure 2. Patients with cardiac pacemaker or other implanted electromedical devices which could interfere with magnetic resonance 3. Suspected or known intestinal stenosis or other known risk factors for capsule retention 4. Patients with dysphagia 5. Pregnancy 6. Allergy to polymeric materials, latex, simethicone, or pronase 7. Patients plan to undergo magnetic resonance imaging examination before excretion of the capsule 8. Patients with any condition that precludes compliance with the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images | Prior to ESD or biopsy |
| Histopathology results | During ESD or biopsy |
Countries
China
Contacts
CONTACTJun Pan, MD
PRINCIPAL_INVESTIGATORJun Pan, MD
Changhai Hospital
Outcome results
None listed