Modified Radical Mastectomy
Conditions
Keywords
magnesium sulphate, bupivacaine, modified radical mastectomy
Brief summary
To compare mean duration of postoperative analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.
Detailed description
There is a difference in mean duration of analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.
Interventions
DRUGGroup B (bupivacaine)
receive 20 ml of 0.25% bupivacaine on the operated side for the Erector Spinae Plane (ESP) block.
DRUGBupivacaine plus magnesium sulfate
20 ml of 0.25% bupivacaine plus 250 mg of magnesium sulfate on each side.
Sponsors
Gulab Devi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Female patients having ASA 1 and Il being aged 2 5 - 60 years and undergoing one sided breast cancer surgery \* Patients who sign written informed consent to participate in the study.
Exclusion criteria
* Patients having contraindications for regional blocks (c.g., infection a t the injection site, coagulopathy), allergy to the drugs used i n the study Patients who received radiotherapy, and patients need axillary dissection • Patients with known hypersensitivity to local anesthetic drug (Bupivacaine). Patients with coagulation disorders or receiving anti-coagulant therapy (INR\>2.0).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| post-operative analgesia | 20 minutes | There is a difference in mean duration of analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients. |
Countries
Pakistan
Outcome results
None listed