Vagus Nerve Stimulation
Conditions
Brief summary
The purpose of this study is to determine the feasibility of using non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) to examine physiological and psychological responses in a college-aged healthy population
Interventions
DEVICEActive taVNS
Actual taVNS
DEVICESham taVNS
No nerve stimulation
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Intervention model description
This is a within-subject, counterbalanced repeated-measures study with two experimental conditions (active taVNS and sham taVNS)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Participants must be between the ages of 18 and 35 as we are focused on recruiting undergraduate and graduate students.
Exclusion criteria
* Participants will be excluded if they have epilepsy, clinically significant tachycardia or arrhythmia, diabetes (Type 1 or Type 2) or another metabolic disease, current pregnancy, any implanted electronic medical device (for example, pacemaker or defibrillator), or a known skin allergy to adhesives that would prevent CGM placement. Participants will also be excluded if they have a history of major depressive disorder if taVNS could reasonably be expected to alter mood symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in plasma glucose | Hour 2 after oral glucose load |
Countries
United States
Contacts
CONTACTMark Hartman, PhD
PRINCIPAL_INVESTIGATORMark Hartman, PhD
University of Minnesota
Outcome results
None listed