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Development and Validation of a Multimodal Artificial Intelligence Model for Early Prediction of Acute Myocardial Infarction

Development and Validation of a Multimodal Artificial Intelligence Model for Early Prediction of Acute Myocardial Infarction

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07457320
Enrollment
1500
Registered
2026-03-09
Start date
2026-04-01
Completion date
2028-12-01
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction

Brief summary

Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide. Although early revascularization has markedly improved short-term outcomes, the incidence of major adverse cardiovascular events after the index event remains unacceptably high, posing a formidable clinical challenge. Contemporary risk-stratification instruments rely predominantly on a restricted set of conventional clinical variables and therefore fail to capture the full spectrum of individual pathophysiological complexity. To overcome these limitations, the present investigation aims to develop a post-AMI prognostic model that integrates comprehensive multimodal data.

Interventions

PROCEDUREPercutaneous coronary intervention

Percutaneous coronary intervention

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Age ≥18 years old 2. Presented with myocardial infarction, including NSTEMI and STEMI 3. Undergoing successful percutaneous coronary intervention.

Exclusion criteria

1.Poor imaging quality or a data missing rate \>30%

Design outcomes

Primary

MeasureTime frameDescription
Diagnostic performance6 monthsthe diagnostic performance (AUC) for predicting the risk of acute myocardial infarction (AMI) within 6 months

Countries

China

Contacts

CONTACTJun Jiang, MD
21918219@zju.edu.cn+86 15657125311

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026