Focus on Axial Length
Conditions
Brief summary
In this study, atropine 0.01% eye drops will be given to myopic children once at night daily for 6 months as compared to a control group to see the effect on axial length and refraction
Interventions
DRUGAtropine 0.01% eye drops
Eye drops atropine 0.01% given once nightly to group A for 6 months
Sponsors
Liaquat National Hospital & Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
4 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* Children aged 4-16 years * Both genders * Myopia of baseline SER of -1.00D or more * Astigmatism less than or equal to -2.50D * No medical history predisposing severe myopia (e.g., Marfan syndrome, Stickler syndrome, and retinopathy of prematurity), abnormal ocular refractive anatomy (e.g., keratoconus, lenticonus, and spherophakia) * No history of other vision-threatening ocular diseases or previous intraocular surgery. * No current or previous use of atropine or pirenzipine, contact lenses or other forms of treatment that may affect myopia progression.
Exclusion criteria
* Astigmatism ≥ 2.5 D * Anisometropia\>1 D * Best corrected visual acuity \< 0.5 (6/12) * Prior intraocular surgery * Allergy to atropine eye drops * Systemic diseases associated with myopia such as Marfan syndrome, Stickler syndrome * History of cardiac or significant respiratory diseases * Lack of consent for participating in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in axial length in mm | 6 months | Axial length is measured at the time of recruiting the participants and after the end of study |
| Change in refraction in Diopters | 6 months | Refraction is measured at the start of study then after 6 months of study |
Countries
Pakistan
Contacts
CONTACTHina Nadeem, MBBS
PRINCIPAL_INVESTIGATORHina Nadeem, MBBS
LNHMC
Outcome results
None listed