Squamous Cell Carcinoma of the Anal Canal, HPV-induced Cancer
Conditions
Brief summary
This study examines care pathways in 300 patients with anal squamous cell carcinoma to identify barriers and delays in diagnosis, assess the impact of screening and access to care, and improve awareness, screening practices, and early diagnosis.
Detailed description
This situational analysis will make it possible to identify barriers and delays in diagnosis, to assess waiting times for access to consultations, and to evaluate the existence of potential fast-track diagnostic pathways. It will analyze the proportion of cancers diagnosed through screening as well as the proportion of eligible patients who did not benefit from screening. Assessing patient reluctance, the impact of socio-economic conditions, and patients' knowledge of the link between HPV and anal cancer will help better target public information efforts. Ultimately, the aim of the study is to improve care pathways in order to enhance public and healthcare professional awareness and promote earlier diagnosis.
Interventions
Completion of a self-administered questionnaire by the patient to collect information about their care journey, any difficulties or hesitations, as well as their knowledge of the link between papillomavirus and cancer.
Sponsors
Centre Hospitalier Intercommunal Creteil
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Male or female ≥ 18 years 2. Histologically proven invasive or microinvasive squamous cell carcinoma of the anus 3. Having read and understood the information letter provided, either: i. After disclosure of the diagnosis, or ii. At the latest 6 months after initiation of treatment (surgical excision, radiotherapy, or chemoradiotherapy) 4. Affiliated with a social security system
Exclusion criteria
1. Refusal to participate in the protocol 2. Other histological types: lymphoma, adenocarcinoma, neuroendocrine tumor, etc. 3. Time since treatment initiation greater than 6 months 4. Protected persons (pregnant women, breastfeeding women, individuals under guardianship or curators, minors, persons deprived of liberty, or persons unable to express informed consent).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| First symptom(s) and the histological diagnosis | At the inclusion | Time between the first symptom(s) and the histological diagnosis of anal squamous cell carcinoma. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Primary tumor, regional nodes, metastasis (TNM) ) stage comparison | At the inclusion | Comparison of diagnostic stages and patient pathways according to whether or not they underwent scr |
| Assessment of Deprivation and Health Inequalities for Health Examination Centers, French | At the inclusion | French public-health index used to assess an individual's level of social and material deprivation based on living conditions, financial situation, social support, and access to healthcare. It helps identify social health inequalities and adapt medical care accordingly. \[0 to 100\], The higher the score → the greater the level of deprivation. |
| Link between HPV and anal cancer | At the inclusion | Proportion of patients aware of the link between HPV and anal cancer |
| Performing a rectal examination at the first consultation | At the inclusion | Assess the proportion of patients who underwent a clinical examination with rectal examination at the first consultation |
Contacts
CONTACTISABELLE ETIENNEY
Outcome results
None listed