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Preoperative Cardiac Power Output and P-POSSUM Score

Investigation of the Relationship Between Preoperative Cardiac Power Output and P-POSSUM Score

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07454564
Enrollment
120
Registered
2026-03-06
Start date
2026-03-10
Completion date
2026-11-30
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Morbidity, Postoperative Mortality, Surgical Risk Assessment

Keywords

p-possum score, cardiac power output

Brief summary

This study aims to investigate the relationship between preoperative Cardiac Power Output (CPO), which reflects the pumping capacity of the heart, and the P-POSSUM score, a widely used surgical risk assessment tool, in patients aged 65 years and older undergoing abdominal surgery. Simple and non-invasive measurements performed in the preoperative period will be used to obtain CPO values and to evaluate whether these measurements are helpful in predicting postoperative morbidity and mortality. No additional procedures beyond routine clinical care will be performed as part of this observational study. The findings of this study may contribute to a more accurate assessment of surgical risk and help improve patient safety in the perioperative period.

Detailed description

This is a prospective, observational study designed to evaluate the relationship between preoperative Cardiac Power Output (CPO) and the P-POSSUM risk score in patients aged 65 years and older undergoing abdominal surgery, including both elective and emergency procedures. CPO is a hemodynamic parameter reflecting overall cardiac pumping power and may provide additional physiologic information beyond traditional risk models. P-POSSUM is widely used to estimate postoperative morbidity and mortality based on physiological and operative variables. Eligible patients will be assessed in the preoperative period. Preoperative CPO will be obtained using non-invasive hemodynamic measurements as part of routine perioperative practice. The P-POSSUM score will be calculated for each patient using standard definitions. Patients will be followed during the postoperative period to document clinical outcomes, including postoperative complications and mortality within the predefined follow-up window, as well as length of hospital stay when available. The primary objective is to assess the association between preoperative CPO and the P-POSSUM score. Secondary objectives include exploring whether preoperative CPO is associated with postoperative outcomes and whether it may help refine perioperative risk stratification. This study does not involve any investigational treatment; no additional interventions beyond standard clinical care will be performed. All data will be handled in accordance with applicable privacy and confidentiality regulations, and patient identifiers will not be included in the analysis dataset.

Interventions

None listed

Sponsors

Necmettin Erbakan University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Being 65 years of age or older, * Undergoing abdominal surgery in general surgery practice (including elective and emergency procedures), * ASA (American Society of Anesthesiologists) class I-III, * Adequate recording with transthoracic echocardiography, * Having given informed consent.

Exclusion criteria

Advanced heart failure with ejection fraction (EF) \<30%, * Severe valvular disease (severe stenosis or insufficiency), * Unstable coronary artery disease or recent myocardial infarction (within the last 3 months), * Pulmonary hypertension, * Severe arrhythmia (uncontrolled atrial fibrillation, ventricular tachycardia, etc.)

Design outcomes

Primary

MeasureTime frameDescription
30-day postoperative mortalityUp to 30 days after surgeryAll-cause mortality occurring within 30 days after abdominal surgery in patients aged 65 years and older (yes/no).

Secondary

MeasureTime frameDescription
Postoperative morbidityUp to 30 days after surgeryPostoperative morbidity assessed using the Postoperative Morbidity Survey (POMS).
Early postoperative morbidityPostoperative day 3Early postoperative morbidity assessed using the Postoperative Morbidity Survey (POMS) on postoperative day 3.

Countries

Turkey (Türkiye)

Contacts

CONTACTEngin Kılınç, Medical Doctor
enginkilinc96@gmail.com00 90 332 223 60 00
PRINCIPAL_INVESTIGATORŞULE ARICAN, Assoc. Prof.

Konya Necmettin Erbakan University

STUDY_DIRECTOREngin Kılınç, Medical Doctor

Konya Necmettin Erbakan University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 24, 2026