Mandible Reconstruction
Conditions
Brief summary
The goal of this clinical trial is to learn if mandibular reconstruction with immediate dental implants is as accurate in fresh cases and delayed cases The accuracy of the fibular segments and dental implants will be compared in both groups Participants will: undergo a preoperative CT scan with VSP for mandibular reconstruction Undergo the surgical procedure Undergo an immediate postoperative CT scan and have it superimposed on the virtual plan to detect inaccuracies
Detailed description
The goal of this clinical trial is to learn if mandibular reconstruction with immediate dental implants is as accurate in fresh cases and delayed cases The accuracy of the fibular segments and dental implants will be compared in both groups Participants will: undergo a preoperative CT scan with VSP for mandibular reconstruction Undergo the surgical procedure Undergo an immediate postoperative CT scan and have it superimposed on the virtual plan to detect inaccuracies
Interventions
PROCEDUREfibula free flap
Immediate reconstruction with the use of PSIs and dental implants in fresh and delayed cases
Sponsors
Cairo University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
for participants: * Adult patients with conditions requiring mandibular reconstruction using fibula free flaps. * Adult patients diagnosed with neoplastic conditions requiring resection and agreed to immediate reconstruction * Adult patients with segmental mandibular defects resulting from previous pathology, trauma, infectious conditions * Patients willing for the surgical procedure and follow-up, with an informed consent.
Exclusion criteria
for participants: * Patients with significant medical diseases and comorbidities preventing them undergoing lengthy procedures under general anesthesia * Patients with Peripheral Vascular Disease * Patient with known allergy to contrast media in whom a CTA of the lower limbs will not be possible * Patients with Peronea Magna where the peroneal artery is the main blood supply of the lower limbs and its harvesting might result in compromise of the leg vascularity * Patients with no desire for surgical correction * Patients with any diseases that compromise bone or soft tissue healing. Patients with local pathosis that interfere with the bone healing.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of the fibular segments and dental implants | From enrollment "VSP" till the immediate postoperative CT, Throughout the completion of the study, for an average of 1 year | Accuracy of the fibular segments and dental implants in patients compared to the Virtual Surgical plan, Measured in degrees and millimeters |
Countries
Egypt
Outcome results
None listed