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Chronic Total Occlusion and Triglyceride-Glucose Index

The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07451860
Enrollment
200
Registered
2026-03-05
Start date
2026-03-15
Completion date
2026-09-15
Last updated
2026-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CAD - Coronary Artery Disease, Chronic Total Occlusion (CTO), Triglycerid Glucose Index

Brief summary

We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.

Interventions

DIAGNOSTIC_TESTtriglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.

As no previous studies have demonstrated the predictive value of the TyG index for chronic total occlusion (CTO), the present investigation provides a novel contribution to the literature. We hypothesize that the triglyceride-glucose (TyG) index will be significantly higher in patients with chronic total occlusion (CTO) compared to those without CTO.

Sponsors

Kırıkkale University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals

Exclusion criteria

* Patients \<18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI \>30 kg/m²), inaccessible patient records

Design outcomes

Primary

MeasureTime frame
The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples.1 Year

Countries

Turkey (Türkiye)

Contacts

CONTACTRUKİYE GÖNEN ÖZDEMİR
rukiye_gonen@hotmail.com+905054503953

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 6, 2026