Solid Tumor
Conditions
Keywords
Proton Therapy, fully digital PET, in-beam online monitoring
Brief summary
The energy transport process of proton beams after entering biological tissue is observed online via proton knife fully digital PET. The dynamic changes of the delivered dose and action range of proton beams in biological tissue are analyzed, the proton dose distribution is reconstructed, and the energy and position of the targeted ablation by proton beams are determined, so as to realize in-beam online PET monitoring for proton therapy.
Interventions
RADIATIONproton therapy
proton therapy
Sponsors
Shuanghu Yuan
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Patients with solid tumors scheduled to receive proton therapy, with measurable lesions; 2. Signed the informed consent form.
Exclusion criteria
1. Patients with a history of radioactive seed implantation; 2. Patients who cannot understand the purpose of treatment or are unwilling/unable to sign the informed consent form;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the trajectory and range of the proton beam within the human body | 1 day | the three-dimensional dynamic distribution of positron nuclides generated by proton beam irradiation |
Countries
China
Contacts
STUDY_CHAIRXiaojing Wang, MD
Anhui Provincial Cancer Hospital
Outcome results
None listed