Epilepsies, Remote Management of Epilepsy in Rural Areas
Conditions
Brief summary
This project, titled "Application of an AI-Based Health Management System in Long-Term Epilepsy Management in Rural Areas ", is led by the First Affiliated Hospital of Air Force Medical University, with Jiang Wen as the principal investigator. It is a prospective, multicenter, cluster-randomized controlled trial involving 756 patients from eight rural counties in China's northwest region. The study aims to evaluate the effectiveness of an AI-assisted remote healthcare system (via a WeChat mini-program) compared to standard care in reducing seizure frequency and improving self-management skills among adult epilepsy patients. Key components include patient and doctor interfaces for features like AI consultations, medication reminders, and online consultations. The trial runs from December 1, 2025, to November 30, 2027, with primary outcomes measured at 12 months and secondary outcomes assessing medication adherence, quality of life, and safety.
Interventions
DEVICEAI-enabled WeChat mini-program "Epilepsy Smart Monitoring and Diagnosis System":
Patient Module: Real-time monitoring, medication reminders, AI consultations, seizure logging, educational resources. Physician Module: AI-assisted diagnostics, online consultations, data analytics dashboard.
Sponsors
Xijing Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Meets ILAE 2017 diagnostic criteria for epilepsy. * ≥1 bilateral tonic-clonic seizure in the past 12 months. * Aged 18-65 years. * Access to a smartphone patient/caregiver. * Written informed consent.
Exclusion criteria
* Pregnancy, lactation, or planned pregnancy. * Seizures with identifiable triggers e.g., alcohol withdrawal. * Allergy to phenobarbital/sodium valproate. * Severe comorbidities e.g., organ dysfunction, malignancy, psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Seizure change | 12 months | Evaluation method: Calculate by comparing the frequency of attacks during the baseline period (12 months before enrollment) with the monthly average frequency of attacks during the intervention period (12 months) |
| Epilepsy Self Management Scale Score | 12 months | Evaluation method: The Chinese version of the Epilepsy Self Management Scale was used. This scale includes multiple dimensions (such as drug management, information management, safety management, etc.), and a higher total score indicates stronger self-management ability. |
Countries
China
Outcome results
None listed