Obesity, Obstructive Sleep Apnea, Primary Open Angle Glaucoma
Conditions
Brief summary
glaucoma is prevalent among obstructive sleep apnea (OSA). contnous passive airway pressure is main treatment of OSA. lifestyle corrections also recommended
Detailed description
forty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved and divided to group I or group II (number of patients will be twenty in every group) for three month. both groups will apply CPAP during night sleeping daily for three month. group I will apply lifestyle corrections (low calories diet intake and 3-session per-week 40-minute treadmill walking for three month.
Interventions
OTHERCPAP
twenty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved in group II will apply CPAP during night sleeping daily for three month.
BEHAVIORALlifetyle corrections and CPAP
twenty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved in group I will apply CPAP during night sleeping daily for three month. group I will apply lifestyle corrections (low calories diet intake and 3-session per-week 40-minute treadmill walking for three month.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Obstructive sleep apnea patients * obese patients * glaucoma (open angle form with ocular hyoertension)
Exclusion criteria
cardiac patients renal patients hepatic patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure | it will be measured after 12 weeks | it will be measured by tonometery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| apnea hypopnea index | It will be measured after 12 weeks | it is an indicator on numbe rof apnea during sleep |
| Epowrth sleepiness scale | It will be measured after 12 weeks | a questioanire assess rate of sleepiness |
| body mass index | It will be measured after 12 weeks | it assesed on empty bladder and bowel |
| waist circumference | it will be measured after 12 weeks | it will be assesed at umbilical level |
| neck circumferfence | It will be measured after 12 weeks | it is a measures of local fat around neck |
| glaucoma related quality of life questioanire | It will be measured after 12 weeks | it is 15-item questioanire assessing life quality in qlaucoma |
Countries
Egypt
Contacts
CONTACTAli MA Ismail, lecturer
CONTACTali mohamed, lecturer
PRINCIPAL_INVESTIGATORAli MA Ismail, lecturer
Cairo University
Outcome results
None listed