Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material

Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material in Immediate Dental Implant Placement

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07445776

Enrollment

Registered

2026-03-03

Start date

2024-05-01

Completion date

2025-09-01

Last updated

2026-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gap Filling With Allograft, Gap Filling With e-PRF, Immediate Implant Placement

Brief summary

Twenty-eight patients seeking prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant will be selected from the outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University

Interventions

OTHERAllograft

after immediate implant placement the gap will be filled with allograft

OTHERe-PRF

after immediate implant placement the gap will be filled with e-PRF

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients with badly destructed teeth due to trauma or caries. 2. Patients willing to complete the study follow up intervals. 3. Patients with good oral hygiene. 4. Adequate inter-arch space that can accommodate implant abutment and future restoration. 5. No gender preference in selection of the patients.

Exclusion criteria

1. Patients with systemic diseases that absolutely contraindicate dental implant placement. 2. Patients with parafunctional habits (bruxism and clenching). 3. Heavy smokers (i.e. More than 20 cigarettes/day)34 and alcoholism. 4. Presence of local infection or lesions at the proposed area for dental implant. 5. Pregnancy. 6. Patient taking drugs that could affect bone healing process as immunosuppressive drugs and bisphosphonates. 7. Patients with bad oral hygiene and untreated periodontal disease 8. Uncooperative patients

Design outcomes

Primary

Measure	Time frame	Description
Implant stability	immediately ,6months follow up & one year	Resonance frequency analysis (RFA) values expressed as implant stability quotient (ISQ) will be recorded by (Osstell Mentor Device)

Secondary

Measure	Time frame	Description
Marginal bone loss	immeditely,6months follow up & one year	CBCT was done to assess the buccal marginal bone loss

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 1, 2026