Efficacy of Different Modalities on Management of Renal Hard Stones

Comparative Outcomes of FURS, ESWL and Mini-PCNL for Non-Lower Pole Hard Renal Stones: A Prospective Randomized Study.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07445646

Enrollment

300

Registered

2026-03-03

Start date

2021-02-01

Completion date

2023-12-30

Last updated

2026-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stone, Kidney, Urolithiasis

Brief summary

The study has been conducted in Urology department at Kafrelsheikh University Hospital between Feburary 2021 to December 2023. informed consent was taken from eligible patients and were randomized into three groups, Group A :Flexible ureteroscope (F-URS) group underwent holmium laser lithotripsy using flexible ureteroscopy (Boston® scientific (lithovue) while, Group B : extracorporeal shock wave lithotripsy (ESWL) group underwent electromagnetic extracorporeal shock wave lithotripsy (STORZ® MEDICAL Modulith SLX-F2 FD21, Germany) .Group C : Mini perc group underwent holmium laser lithotripsy using Karl® Storz MIP set.

Interventions

PROCEDURELithotripsy using Flexible ureteroscope

using Flexible ureteroscope and holmium laser lithotripsy to get high stone clearance rate

PROCEDUREExtracorporeal shock wave lithotripsy (ESWL)

using extracorporeal shock wave lithotripsy (ESWL) to get high stone clearance rate

PROCEDUREholmium laser lithotripsy using Karl® Storz MIP

using holmium laser lithotripsy using Karl® Storz MIP set to get high stone clearance rate

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patient older than 18 years. * single renal stone. * medium sized Stone up to 2.0 cm . * Do novo * Stone in plevicalyceal except lower calyceal stone * Hard stone

Exclusion criteria

* multiple renal stones * Stone in lower calyceal stone * stone size \> 2 cm * age group \< 18 * solitary kidney * Patients with BMI \> 40 kg/m2 * bleeding disorders * anatomical renal abnormalities * Obstruction distal to the stone. * Musculoskeletal deformities

Design outcomes

Primary

Measure	Time frame	Description
stone free rate	two weeks from primary procedure	no stone residual fragments or asymptomatic insignificant residual fragments less than or equal to 4 mm during patients follow up two weeks.

Secondary

Measure	Time frame	Description
ssess operative time	during the procedure	assess operative time.in minutes
Radiation time	during the procedure	Time of patient exposure for radiation in minutes
Post operative complication	Up to 48 hours	Complication may occur post operative complication like fever, sever pain

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 18, 2026