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Gingival Recessions in Orthodontically Treated and Untreated Adult Patients

Gingival Recessions in Orthodontically Treated and Untreated Adult Patients: a Prospective Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07445555
Enrollment
50
Registered
2026-03-03
Start date
2023-11-15
Completion date
2027-09-01
Last updated
2026-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession, Orthodontic Treatment

Keywords

gingival recession, orthodontic treatment, gingival phenotype, occlusal factors

Brief summary

To identify the predisposing parameters for gingival recessions in adult patients seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival recessions.

Detailed description

The etiology of gingival recessions is yet to be fully understood and is very likely multifactorial, with the involved parameters not necessarily acting simultaneously or in equal extent. The most common etiologic factor would be dental plaque accumulation followed by traumatic tooth brushing, areas with thin, minimal or no keratinized tissue, smoking, malocclusion, dental trauma and high frenal attachment. The labial aspect of the mandibular incisors and maxillary molars is the most often affected by gingival recessions. These contributing factors identified in literature could be grouped in six main categories: age-related, population-related, site-related, mechanical factors, periodontal condition and iatrogenic factors, like orthodontic treatment. Although quantifying the influence of each factor is very difficult, the association between gingival recessions and orthodontic treatment as an iatrogenic factor has been repeatedly suggested. Given the increasing amount of adult patients seeking orthodontic treatment, the aim of this study is to identify the predisposing parameters for gingival recessions in adult patients, seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival recessions.

Interventions

OTHERRegistration of parameters

De gingival and occlusal parameters will be recorded for the 4 different cohort groups

Sponsors

Universitaire Ziekenhuizen KU Leuven
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients with or without previous history of orthodontic treatment with and without gingival recessions * ≥ 18 years old * American Society of Anesthesiologists Classification I or II

Exclusion criteria

* Patients with history of periodontal disease * taking the following medication: anticoagulants, phenytoin, cyclosporine, nifedipine or calcium channel blockers * Patients with prior history of radio or chemotherapy * Pregnant or breastfeeding patients * Patients with agenesis of one or more lower incisors

Design outcomes

Primary

MeasureTime frameDescription
Gingival parameters6 monthsPresence of Recessions (Location and extension): in mm (0 to 9)
Periodontal phenotype:6 monthsmeasured from 0.01 to 9.00 (Biometric Ultrasound Scanner)
Full Mouth Bleeding scores (FMBS)6 monthsIn % of total sites (0 to 100)
Full Mouth Plaque Score (FMPS)6 monthsIn % of total sites (0 to 100)
Occlusion6 monthsAssessed as: N.A, 1 DO, 3/4 DO, 1/2 DO,1/4 DO, NO, 1/4 MO, 1/2 MO, 3/4 MO, 1 MO
Occlusal contact points6 monthsMeasured in mm ( 0.0 to 3.0)

Countries

Belgium

Contacts

CONTACTAna Castro
ana.castro@uzleuven.be+3216332407
CONTACTMaria Cadenas
maria.cadenas@uzleuven.be+3216332407
PRINCIPAL_INVESTIGATORAna Castro

Universitaire Ziekenhuizen KU Leuven

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026