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Recovery Hypoxemia After Sedated Upper Gastrointestinal Endoscopy

Incidence, Duration, and Clinical Impact of Recovery-Period Hypoxemia Following Sedated Upper Gastrointestinal Endoscopy: A Prospective Observational Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07445256
Enrollment
100
Registered
2026-03-03
Start date
2026-02-28
Completion date
2026-03-20
Last updated
2026-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia

Brief summary

Sedation during upper gastrointestinal endoscopy may lead to respiratory events not only during the procedure but also in the early recovery period. Although most hypoxemic episodes are considered transient, their frequency, duration, and clinical consequences during recovery remain insufficiently defined. This prospective observational study aims to evaluate the incidence, duration, and clinical impact of recovery-period hypoxemia following sedated upper gastrointestinal endoscopy. Hypoxemia is defined as SpO₂ \<90% lasting ≥10 seconds. Associated respiratory events and potential risk factors will be analyzed without altering routine clinical practice.

Interventions

OTHERSedated Upper Gastrointestinal Endoscopy

Routine upper gastrointestinal endoscopy performed under anesthesiologist-administered sedation. No experimental intervention is applied; the study prospectively observes respiratory events during the recovery period as part of standard clinical care.

Sponsors

Istinye University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults aged ≥18 years * Scheduled for upper gastrointestinal endoscopy (EGD) under anesthesiologist-administered sedation * Able to undergo post-procedure monitoring in the recovery unit * Provided written informed consent for participation and data use

Exclusion criteria

* Colonoscopy or combined procedures (EGD + colonoscopy) * Emergency procedures or procedures performed under intensive care conditions * Requirement for endotracheal intubation, noninvasive ventilation, or advanced airway support during the procedure * Known severe upper airway anatomical abnormalities, facial deformity, or tracheostomy * Inability or refusal to provide informed consent * Incomplete or unavailable recovery-period oxygen saturation monitoring data

Design outcomes

Primary

MeasureTime frameDescription
Recovery-Period Respiratory EventsFrom end of procedure (scope-out) until discharge from recovery unitOccurrence of respiratory events during the recovery period following sedated upper gastrointestinal endoscopy, defined as at least one of the following: SpO₂ \<90% lasting ≥10 seconds Requirement for airway maneuver (jaw-thrust, chin-lift, OPA/NPA, mask ventilation) Escalation or re-initiation of supplemental oxygen

Countries

Turkey (Türkiye)

Contacts

CONTACTilke dolgun
ilkeser2004@gmail.com+905555485632

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026