Periodontitis
Conditions
Keywords
Treponema parvum, Subgingival microbiome, Periodontitis
Brief summary
The current study primarily aims to evaluate the presence of T. parvum in periodontal health and disease, and its correlation with clinical parameters. Subgingival plaque samples will be collected using sterile paper points then the samples will be analyzed using quantitative polymerase chain reaction (qPCR) to detect T. parvum and estimate its relative amount in the biofilm. The results may help clarify the association between T. parvum and periodontitis.
Interventions
None listed
Sponsors
University of Baghdad
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
include participants who have at least 20 teeth and diagnosed as generalized periodontitis.
Exclusion criteria
participants meeting any of the following criteria were excluded: (1) undergoing orthodontic treatment; (2) having a history of antibiotic/nonsteroidal anti-inflammatory drugs use within the last three months; (3) having a history of valve replacement who need prophylactic antibiotic coverage; (4) pregnant or lactating women; (5) having a history periodontal therapy within the last six month. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Relative abundance of T. parvum in subgingival biofilm | At enrollment | Detection and relative abundance of T. parvum in subgingival biofilm measured by qPCR from subgingival plaque collected using sterile paper points |
Countries
Iraq
Contacts
CONTACTMays Jaafar Dentist, B.D.S
Outcome results
None listed