Safety and Efficacy in Pain Reduction of CT-Guided Screw Fixation for Post-laminectomy Surgery Segment Spinal Instability: A Monocentric Study of 24 Patients (2023-2026)

Post Laminectomy Spinal Instability: the Role of CT Guided Screw Fixation to Avoid New Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07443267

Enrollment

Registered

2026-03-02

Start date

2023-03-08

Completion date

2026-02-03

Last updated

2026-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Segmental Instability Post-laminectomy

Keywords

Spinal Disease, Adjacent Segment Disease

Brief summary

Segmental instability of the spine following laminectomy or surgical arthrodesis is a common complication that often requires additional surgical intervention. CT-guided trans-facet screw fixation (TFF), performed under local anesthesia, is an innovative and minimally invasive technique that offers an alternative to open surgery under general anesthesia. This study aims to evaluate the effectiveness of CT-guided TFF fixation in reducing pain and improving daily activities in a population of 24 patients who have undergone prior spinal surgeries

Interventions

OTHERNo intervention

No intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

41 Years to 93 Years

Healthy volunteers

Inclusion criteria

* Treated at the University Hospital of Nice between march 2023 and january 2026 with trans-facet arthrodesis for persistent lumbar segment instability following previous laminectomy surgery. * MRI or scintigraphy imaging showed signs suggestive of instability * Newly developed or worsening spondylolisthesis on successive examinations * Congestive arthropathy * Facet dislocation * Inflammatory disc disease (MODIC type 1 changes)

Exclusion criteria

* Inability to tolerate the prone position under local anesthesia. * Presence of anatomical variants precluding the technical feasibility of transfacet fixation.

Design outcomes

Primary

Measure	Time frame	Description
Change in pain levels between pre-intervention and post-intervention measurements.	Baseline) , 1 month post-intervention, 6 months post-intervention, and 1 year post-intervention.	Pain assessed using the Visual Analog Scale (VAS) from 1 to 10,

Secondary

Measure	Time frame	Description
Improvement in quality of life following the intervention.	Baseline ) 1 month post-intervention 6 months post-intervention and 1 year post-intervention.	EQ-5D-3L questionnaire

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 1, 2026