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Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females

The Relationship Between Lower-limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07440615
Enrollment
235
Registered
2026-02-27
Start date
2026-02-20
Completion date
2026-08-15
Last updated
2026-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aerobic Capacity, Anaerobic Power, Jumping Performance in Young Adults, Leg Muscle Mass, Muscle Strength, Physical Performance

Keywords

lean mass, isokinetic, isometric, aerobic capacity, force

Brief summary

The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults. In addition, these physical performance measures will be compared between male and female participants. Recreationally active young adults will be recruited to participate in the study. Body weight and leg muscle mass will be assessed using a body composition analyzer. Participants will perform isokinetic and isometric leg strength tests, an aerobic fitness test (VO₂max), an anaerobic power test (Wingate), and a countermovement jump (CMJ) test. This study aims to improve the understanding of the effects of leg muscle mass on physical performance and to identify possible differences between males and females. The findings are expected to contribute to exercise prescription, performance assessment, and future research in sports and health sciences.

Interventions

Muscle Isokinetic Strength Testing, Leg Muscle Mass, and Aerobic and Anaerobic Performance Testing, Contermovement Jump

Sponsors

Uludag University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* absent of lower body injuries that could impact testing; * were moderately physically active * did not ingest ergogenic aids or stimulant drugs for at least 6 months prior to the start of the study.

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Leg Muscle Mass-Related Physical Performance MeasuresBaselineMeasurement tool: Bioelectrical Impedance Analyzer (InBody 270, Biospace Co., South Korea) Description: Segmental lower-limb muscle mass (kg) measured using multi-frequency bioelectrical impedance analysis. Unit: kg Time Frame: Baseline (single assessment)
Muscle Isokinetic StrengthBaselineMeasurement tool: Isokinetic dynamometer (Humac Norm, Computer Sports Medicine Inc., USA) Description: Peak torque of dominant leg knee flexors and extensors measured at 60°·s-¹ and normalized to body weight. Unit: Nm·kg-¹ Time Frame: Baseline
Anaerobic PowerBaselineMeasurement tool: Wingate Anaerobic Test performed on cycle ergometer (Wattbike WPM Model B, UK) Description: Relative peak anaerobic power calculated during 30-s Wingate test and normalized to body weight. Unit: W·kg-¹ Time Frame: Baseline
Countremovement JumpBaselineMeasurement tool: SmartJump contact mat system (Fusion Sport, Queensland, Australia) Description: Vertical jump height measured during the Countermovement Jump test. Jump height is calculated automatically from flight time using the SmartJump performance measurement system. Scale description: Countermovement Jump Height (centimeters). Typical physiological range in healthy young adults is approximately 10-60 cm. Interpretation: Higher values indicate better lower-body explosive performance. Unit: cm Time Frame: Baseline (up to 8 weeks)
Aerobic CapacityBaselineMeasurement tool: Breath-by-breath metabolic gas analyzer (Cosmed Quark CPET) during Bruce treadmill protocol Description: Maximal oxygen consumption determined according to standard VO₂max criteria. Unit: ml·kg-¹·min-¹ Time Frame: Baseline
Muscle Isometric StrengthBaselineMeasurement tool: Leg dynamometer (Takei T.K.K. 5402, Takei Scientific Instruments, Japan) Description: Maximal voluntary isometric force normalized to body weight. Highest value of three trials recorded. Unit: kg·kg-¹ Time Frame: Baseline

Countries

Turkey (Türkiye)

Contacts

CONTACTTuncay ALPARSLAN, Assoc.Prof.
tuncayalparslan@hotmail.comTürkiye

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 10, 2026